Molecular Weight: 540.92 g/mol

(R)-CR8 trihydrochloride Chemical Structure
Chemical Structure
Check the (R)-CR8 trihydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (184.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol 25 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name (2R)-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]butan-1-ol;trihydrochloride
CAS Number 1786438-30-9
Molecular Formula

C24H29N7O.3ClH

Molecular Weight (MW) 540.92
SMILES Cl.Cl.Cl.CCC(CO)NC1=NC(=C2N=C[N](C(C)C)C2=N1)NCC3=CC=C(C=C3)C4=CC=CC=N4
InChIKey ORYSYXHQFOWNDK-RGFWRHHQSA-N

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Note: Technical data last updated: Sep 1, 2026.