CAS No. 6591-63-5

Quinidine hemisulfate hydrate Chemical Structure
Chemical Structure
Check the Quinidine hemisulfate hydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name bis((S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol);sulfuric acid;dihydrate
CAS Number 6591-63-5
Molecular Formula

C20H24N2O2.1/2H2SO4.H2O

Molecular Weight (MW) 391.47
SMILES COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.O.O.OS(=O)(=O)O
InChIKey ZHNFLHYOFXQIOW-AHSOWCEXSA-N

Ordering Information

Biological Activity

Quinidine hemisulfate hydrate is a Class Ia antiarrhythmic agent that acts as a blocker of voltage-gated sodium channels, muscarinic acetylcholine receptors, and potassium channels. By inhibiting inward sodium currents during phase 0 of the cardiac action potential, it decreases membrane excitability, depresses conduction velocity, and prolongs action potential duration. Furthermore, quinidine exhibits antimalarial activity through the disruption of heme detoxification in parasites. [1]

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Note: Technical data last updated: Sep 1, 2026.