CAS No. 152-43-2
Batch:
Purity:99.89
Chemical Structure
Check the
Quinestrol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 152-43-2 | |
|---|---|---|
| Molecular Formula |
C25H32O2 |
|
| Molecular Weight (MW) | 364.52 | |
| SMILES | CC12CCC3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)OC5CCCC5 |
Quinestrol is a synthetic steroidal estrogen that acts as an estrogen receptor agonist. Upon metabolic activation, it binds to nuclear estrogen receptors, activating estrogen receptor signaling pathways to regulate gene expression involved in cellular proliferation and reproductive tissue maintenance. Through these downstream transcriptional pathways, quinestrol exhibits hormonal activity and modulates endocrine functions, making it useful in hormone replacement therapy research and hormone-dependent cancer models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
72 mg/mL
(197.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 72 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.