CAS No. 1472611-44-1
| IUPAC Name | 4-(2-aminoethoxy)-2-N,6-N-bis[4-(2-aminoethoxy)quinolin-2-yl]pyridine-2,6-dicarboxamide;2,2,2-trifluoroacetic acid | |
|---|---|---|
| CAS Number | 1472611-44-1 | |
| Molecular Formula |
C31H32N8O5·C2HF3O2 |
|
| Molecular Weight (MW) | 710.7 | |
| SMILES | C1=CC=C2C(=C1)C(=CC(=N2)NC(=O)C3=CC(=CC(=N3)C(=O)NC4=NC5=CC=CC=C5C(=C4)OCCN)OCCN)OCCN.C(=O)(C(F)(F)F)O | |
| InChIKey | SLFYRKZWSPFGQZ-UHFFFAOYSA-N |
Pyridostatin Trifluoroacetate Salt is a potent stabilizer of DNA G-quadruplex structures that targets genomic regions, including proto-oncogene promoters and telomeres. By binding and stabilizing G-quadruplex DNA, it induces replication-dependent DNA double-strand breaks, triggers DNA damage responses, and inhibits transcription of key oncogenes. This leads to cell cycle arrest, telomere dysfunction, and selective cytotoxicity in cancer cell lines.
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(140.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 30 mg/mL |
| Ethanol | 9 mg/mL |
| DMSO |
100 mg/mL
(140.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 13 mg/mL |
| DMSO |
100 mg/mL
(140.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 30 mg/mL |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Pyridostatin Trifluoroacetate Salt Solubility in DMSO
- Pyridostatin Trifluoroacetate Salt Stock Solution
- Pyridostatin Trifluoroacetate Salt Storage
- Pyridostatin Trifluoroacetate Salt Stability
- Pyridostatin Trifluoroacetate Salt Molecular Weight
- Pyridostatin Trifluoroacetate Salt SMILES
- Pyridostatin Trifluoroacetate Salt Chemical Structure (2D and 3D)
- Pyridostatin Trifluoroacetate Salt SDS｜MSDS