CAS No. 1472611-44-1
Batch:
Purity:99.01
Chemical Structure
Check the
Pyridostatin Trifluoroacetate Salt
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 4-(2-aminoethoxy)-2-N,6-N-bis[4-(2-aminoethoxy)quinolin-2-yl]pyridine-2,6-dicarboxamide;2,2,2-trifluoroacetic acid | |
|---|---|---|
| CAS Number | 1472611-44-1 | |
| Molecular Formula |
C31H32N8O5·C2HF3O2 |
|
| Molecular Weight (MW) | 710.7 | |
| SMILES | C1=CC=C2C(=C1)C(=CC(=N2)NC(=O)C3=CC(=CC(=N3)C(=O)NC4=NC5=CC=CC=C5C(=C4)OCCN)OCCN)OCCN.C(=O)(C(F)(F)F)O | |
| InChIKey | SLFYRKZWSPFGQZ-UHFFFAOYSA-N |
Biological Activity
Pyridostatin Trifluoroacetate Salt is a potent stabilizer of DNA G-quadruplex structures that targets genomic regions, including proto-oncogene promoters and telomeres. By binding and stabilizing G-quadruplex DNA, it induces replication-dependent DNA double-strand breaks, triggers DNA damage responses, and inhibits transcription of key oncogenes. This leads to cell cycle arrest, telomere dysfunction, and selective cytotoxicity in cancer cell lines.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(140.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 30 mg/mL |
| Ethanol | 9 mg/mL |
| DMSO |
100 mg/mL
(140.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 13 mg/mL |
| DMSO |
100 mg/mL
(140.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 30 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Jump to
- Pyridostatin Trifluoroacetate Salt Solubility in DMSO
- Pyridostatin Trifluoroacetate Salt Stock Solution
- Pyridostatin Trifluoroacetate Salt Storage
- Pyridostatin Trifluoroacetate Salt Stability
- Pyridostatin Trifluoroacetate Salt Molecular Weight
- Pyridostatin Trifluoroacetate Salt SMILES
- Pyridostatin Trifluoroacetate Salt Chemical Structure (2D and 3D)
- Pyridostatin Trifluoroacetate Salt SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.