CAS No. 82508-31-4

Batch: Purity:99.90
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Pseudolaric Acid B Chemical Structure
Chemical Structure
Check the Pseudolaric Acid B product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2E,4E)-5-[(1R,7S,8S,9R)-7-acetyloxy-4-methoxycarbonyl-9-methyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-en-9-yl]-2-methylpenta-2,4-dienoic acid
CAS Number 82508-31-4
Molecular Formula

C23H28O8
Molecular Weight (MW) 432.46
SMILES CC(=CC=CC1(C2CCC3(C2(CCC(=CC3)C(=O)OC)OC(=O)C)C(=O)O1)C)C(=O)O
InChIKey VDGOFNMYZYBUDT-YDRCMHEVSA-N

Ordering Information

Biological Activity

Pseudolaric Acid B is a natural diterpenoid compound that functions as a potent microtubule-destabilizing agent. By disrupting tubulin polymerization and microtubule network dynamics, it arrests the cell cycle at the G2/M phase and triggers apoptotic signaling pathways. These downstream effects result in the suppression of cell proliferation and the induction of apoptotic cell death in fungal and cancer cell models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 86 mg/mL (198.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 86 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.