CAS No. 57-55-6

Batch: Purity:
1,2-Propanediol Chemical Structure
Chemical Structure
Check the 1,2-Propanediol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 57-55-6
Molecular Formula

C3H8O2
Molecular Weight (MW) 76.09
SMILES CC(CO)O

Ordering Information

Biological Activity

1,2-Propanediol is a synthetic small-molecule liquid and widely used pharmaceutical excipient, drug carrier, and solvent. It serves as a solubilizing vehicle for poorly water-soluble bioactive compounds in chemical biology, pharmacology, and formulations. Metabolism of 1,2-propanediol proceeds primarily via hepatic alcohol dehydrogenase into lactate, pyruvate, and acetate, thereby providing a low-toxicity medium for drug delivery, food products, and cosmetic preparations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.