CAS No. 84-02-6

Batch: Purity:99.83
Check CoA
Prochlorperazine dimaleate salt Chemical Structure
Chemical Structure
Check the Prochlorperazine dimaleate salt product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 84-02-6
Molecular Formula

C20H24ClN3S.C8H8O8
Molecular Weight (MW) 606.09
SMILES CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O

Ordering Information

Biological Activity

Prochlorperazine dimaleate salt is a dopamine D2 receptor antagonist. Blockade of dopamine D2 receptors attenuates dopaminergic signaling via G protein-coupled pathways, leading to downstream inhibition of adenylyl cyclase activity and modulation of intracellular cyclic AMP levels. This blockade suppresses dopamine-mediated neurotransmission in the central nervous system, producing antiemetic and antipsychotic phenotypes in cell and animal models.

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 27 mg/mL (44.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.