CAS No. 20347-71-1

Batch: Purity:100.00
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Proanthocyanidins Chemical Structure
Chemical Structure
Check the Proanthocyanidins product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 20347-71-1
Molecular Formula

C30H26O13
Molecular Weight (MW) 594.52

Biological Activity

Proanthocyanidins are naturally occurring polyphenolic compounds that act as potent antioxidants and free radical scavengers. They mitigate oxidative stress by reducing intracellular reactive oxygen species (ROS) levels and inhibiting lipid peroxidation. Downstream, proanthocyanidins modulate key cellular signaling cascades, including the NF-kB and MAPK pathways, thereby suppressing pro-inflammatory cytokine expression and protecting cells against oxidative damage and apoptosis. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (168.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Reference

[1] Bagchi D, et al. Toxicology. 2000;148(2-3):187-97.

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Note: Technical data last updated: Sep 1, 2026.