CAS No. 81131-70-6
Batch:
Purity:99.94
Chemical Structure
Check the
Pravastatin (CS-514) Sodium
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | sodium (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate | |
|---|---|---|
| CAS Number | 81131-70-6 | |
| Molecular Formula |
C23H35O7.Na |
|
| Molecular Weight (MW) | 446.51 | |
| SMILES | CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)[O-])O)O)O.[Na+] | |
| InChIKey | VWBQYTRBTXKKOG-IYNICTALSA-M |
Pravastatin sodium (CS-514) is a competitive HMG-CoA reductase inhibitor that suppresses sterol synthesis with an IC50 of 5.6 μM. By blocking the conversion of HMG-CoA to mevalonate within the mevalonate pathway, it reduces downstream cholesterol biosynthesis and isoprenoid production. This pathway inhibition disrupts cellular lipid homeostasis, alters protein prenylation, and modulates vascular endothelial function in preclinical cell models.[1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
89 mg/mL
(199.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 89 mg/mL |
| Ethanol | 89 mg/mL |
| DMSO |
89 mg/mL
(199.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 89 mg/mL |
| Ethanol | 45 mg/mL |
| DMSO |
89 mg/mL
(199.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 89 mg/mL |
| Ethanol | 89 mg/mL |
| DMSO |
89 mg/mL
(199.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 89 mg/mL |
| Ethanol | 89 mg/mL |
| DMSO |
89 mg/mL
(199.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 89 mg/mL |
| Ethanol | 89 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Pravastatin (CS-514) Sodium Clinical Trials
- Pravastatin (CS-514) Sodium Solubility in DMSO
- Pravastatin (CS-514) Sodium Stock Solution
- Pravastatin (CS-514) Sodium Storage
- Pravastatin (CS-514) Sodium Stability
- Pravastatin (CS-514) Sodium Molecular Weight
- Pravastatin (CS-514) Sodium SMILES
- Pravastatin (CS-514) Sodium Chemical Structure (2D and 3D)
- Pravastatin (CS-514) Sodium SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.