CAS No. 104632-25-9
Batch:
Purity:98
Chemical Structure
Check the
Pramipexole dihydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 104632-25-9 | |
|---|---|---|
| Molecular Formula |
C10H17N3S.2HCl |
|
| Molecular Weight (MW) | 284.25 | |
| SMILES | CCCNC1CCC2=C(C1)SC(=N2)N.Cl.Cl |
Pramipexole dihydrochloride is a non-ergoline dopamine agonist that potently targets the D3 receptor, D2L receptor, D2S receptor, and D4 receptor. By activating presynaptic and postsynaptic dopamine receptor pathways, it modulates dopaminergic neurotransmission and inhibits intracellular cyclic AMP accumulation. This agonist activity restores striatal dopaminergic signaling and reduces neurotoxin-induced motor deficits in rodent models of dopaminergic dysfunction. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
56 mg/mL
(197.0 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Pramipexole dihydrochloride Solubility in DMSO
- Pramipexole dihydrochloride Stock Solution
- Pramipexole dihydrochloride Storage
- Pramipexole dihydrochloride Stability
- Pramipexole dihydrochloride Molecular Weight
- Pramipexole dihydrochloride SMILES
- Pramipexole dihydrochloride Chemical Structure (2D and 3D)
- Pramipexole dihydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.