Home Biosimilar Antibodies Others Others Ponsegromab (Anti-GDF15 / MIC-1)
For research use only. Not for use in humans.

Ponsegromab (Anti-GDF15 / MIC-1)

Synonyms: PF 06946860

Ponsegromab (Anti-GDF15 / MIC-1) is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers. MW: 145.5 KD.

Ponsegromab (Anti-GDF15 / MIC-1)

Quality Control

Batch: Purity: 99% Protein concentration: 10.518mg/ml Endotoxin Level: ＜1EU/mg
99

Mechanism of Action

Description
Ponsegromab (Anti-GDF15 / MIC-1) is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers. MW: 145.5 KD.

Product Details

CAS No. 2368950-15-4
Molecular Weight 145.5 kDa
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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Handling Instructions

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