SMILES:

CC(=O)NC(CC1=CC=CC=C1)C(=O)NC2CCCNC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=C[NH]C4=CC=CC=C34)NC(=O)C(CC5CCCCC5)NC(=O)C6CCCN6C2=O
PMX-53 Chemical Structure
Chemical Structure
Check the PMX-53 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2S)-2-acetamido-N-[(3S,9S,12S,15R,18S)-15-(cyclohexylmethyl)-9-[3-(diaminomethylideneamino)propyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7,10,13,16-pentazabicyclo[16.3.0]henicosan-3-yl]-3-phenylpropanamide
CAS Number 219639-75-5
Molecular Formula

C47H65N11O7
Molecular Weight (MW) 896.09
SMILES CC(=O)NC(CC1=CC=CC=C1)C(=O)NC2CCCNC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=C[NH]C4=CC=CC=C34)NC(=O)C(CC5CCCCC5)NC(=O)C6CCCN6C2=O
InChIKey YOKBGCTZYPOSQM-HPSWDUTRSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (111.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.