PLX5622 is a potent, highly selective, and brain-penetrant CSF1R antagonist. It affects neuroinflammatory and microglial survival signaling by blocking CSF1R, effectively depleting microglia and suppressing neuroinflammation.
PLX5622: Mechanism of Action
PLX5622 MOA：Targeting CSF1R/CSF1R Signaling Pathway for Neurodegenerative Diseases