For research use only. Not for use in humans.

Plozalizumab (Anti-CCR2 / CD192)

Synonyms: MLN-1202 Cat.No.A2569 Purity:99%

Plozalizumab (Anti-CCR2 / CD192) is a specific humanized monoclonal antibody targeting CCR2. Plozalizumab can be used for malignant melanoma research. MW:145.5 KD.

Plozalizumab (Anti-CCR2 / CD192)

Click to purchase the isotype control of Plozalizumab (Anti-CCR2 / CD192)

Quality Control

Batch: Purity: 99% Protein concentration: 9.994mg/ml Endotoxin Level: ＜1EU/mg

99

Specificity

Name	Citation	CCR	CCR1	CCR2	CCR3	CCR4	CCR5	CCR9	CCL	Others
SB-328437	0				++
INCB3344	5			++						mCCR2
RS504393	1			+
C-021	0					+
Vercirnon	0							+++
BX471	2		++++
PF-4136309	1			++
Vicriviroc maleate	1	+++					+++
RS-102895 Hydrochloride	0			+						human α1a receptor,human α1d receptor,5-HT1a receptor
RS102895	2			+
TAK-779	0	++++					++++			CXCR3
AZD2098	1					++
Adaptavir (DAPTA)	3	++++					++++
R243	1	✔
Perillaldehyde	1								✔	NRF2/HO1,ROS,AhR
Cenicriviroc	8			✔						HIV-2,HIV-1
Isuzinaxib (APX-115 free base)	0								✔	TNFα,IL-6,NOX2
SB-297006	2				✔
BMS-813160	2			✔
Bindarit (AF2838)	23								✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Plozalizumab (Anti-CCR2 / CD192) is a specific humanized monoclonal antibody targeting CCR2. Plozalizumab can be used for malignant melanoma research. MW:145.5 KD.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1610761-46-0
Molecular Weight	150 kDa
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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