SMILES:

CC(C)CC1(O)CCN(CC1)C(=O)C2=CC=C(N[S;v6](=O)(=O)C3=CC=CC4=C3N=CC=N4)C=C2
PKR-IN-2 Chemical Structure
Chemical Structure
Check the PKR-IN-2 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-[4-[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]phenyl]quinoxaline-5-sulfonamide
CAS Number 1628428-01-2
Molecular Formula

C24H28N4O4S
Molecular Weight (MW) 468.57
SMILES CC(C)CC1(O)CCN(CC1)C(=O)C2=CC=C(N[S;v6](=O)(=O)C3=CC=CC4=C3N=CC=N4)C=C2
InChIKey JTGUGSWLWPKCGF-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 94 mg/mL (200.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 1 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.