Home Biosimilar Antibodies Immunology & Inflammation CD markers Pinatuzumab (Anti-Siglec-2 / CD22)
For research use only. Not for use in humans.

Pinatuzumab (Anti-Siglec-2 / CD22)

Synonyms: Siglec-2， BL-CAM

Pinatuzumab (Anti-Siglec-2 / CD22)a humanized IgG1 monoclonal antibody targeting CD22. It has potential antineoplastic activity and can be used in research of Non-Hodgkin Lymphoma. MW : 146.64 KD.

Pinatuzumab (Anti-Siglec-2 / CD22)

Quality Control

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99

Specificity

Name Citation CD38 CD45 CD39 CD88 CD73 Others
RBN013209 0
MK-0159 0
CD38 inhibitor 1 (compound 78c) 7
AB680 1
NQ301 1 TXA2 receptor
SodiuM Metatungstate 3
PMX-53 3
LY-3475070 2
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Pinatuzumab (Anti-Siglec-2 / CD22)a humanized IgG1 monoclonal antibody targeting CD22. It has potential antineoplastic activity and can be used in research of Non-Hodgkin Lymphoma. MW : 146.64 KD.
References

Product Details

CAS No. 1313706-14-7
Isotype Human IgG1
Source CHO
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT06343090 RECRUITING Drug: CD19 CAR T-cell|Drug: CD22 CAR T cells B-cell Acute Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia, in Relapse; Refractory Acute Lymphoid Leukemia Beijing GoBroad Hospital 2024-04-12
NCT02650414 ACTIVE_NOT_RECRUITING B Cell Leukemias; B Cell Lymphomas University of Pennsylvania 2016-01-13 PHASE1
NCT04815356 RECRUITING Hairy Cell Leukemia; Hairy Cell Leukemia Variant National Cancer Institute (NCI) 2022-05-23 PHASE1
NCT03620058 ACTIVE_NOT_RECRUITING Chemotherapy Resistant Acute Lymphoblastic Leukemia; Refractory Acute Lymphoblastic Leukemia University of Pennsylvania 2018-09-27 PHASE1
NCT06340737 RECRUITING Drug: CD22CART Infusion Follicular Lymphoma; Mantle Cell Lymphoma; Hairy Cell Leukemia; Lymphoplasmacytic Lymphoma; Burkitt Lymphoma; Marginal Zone Lymphoma; Waldenstrom Macroglobulinemia; Large B-cell Lymphoma Stanford University 2024-03-29 PHASE1
NCT06709469 RECRUITING Precursor Cell Lymphoblastic Leukemia-Lymphoma Instituto de Investigación Hospital Universitario La Paz 2025-07-08 PHASE1

(data from https://clinicaltrials.gov, updated on 2026-03-10)

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