CAS No. 27409-30-9

Batch: Purity:99.73
Picroside I Chemical Structure
Chemical Structure
Check the Picroside I product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 27409-30-9
Molecular Formula

C24H28O11

Molecular Weight (MW) 492.47
SMILES C1=CC=C(C=C1)C=CC(=O)OCC2C(C(C(C(O2)OC3C4C(C=CO3)C(C5C4(O5)CO)O)O)O)O

Ordering Information

Biological Activity

Picroside I is a natural iridoid glycoside that acts as a hepatoprotective and antimicrobial agent. It modulates oxidative stress and inflammatory signaling pathways, including NF-kB signaling, to suppress downstream pro-inflammatory cytokines and lipid peroxidation. Through these mechanisms, Picroside I protects hepatic cells against toxin-induced cell injury and demonstrates inhibitory activity against viral and bacterial pathogens. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 98 mg/mL (198.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.