CAS No. 156-51-4

Batch: Purity:99.92
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Phenelzine sulfate Chemical Structure
Chemical Structure
Check the Phenelzine sulfate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-phenylethylhydrazine;sulfuric acid
CAS Number 156-51-4
Molecular Formula

C8H12N2.H2O4S
Molecular Weight (MW) 234.27
SMILES NNCCC1=CC=CC=C1.O[S](O)(=O)=O
InChIKey RXBKMJIPNDOHFR-UHFFFAOYSA-N

Ordering Information

Biological Activity

Phenelzine sulfate is a hydrazine derivative that acts as a potent non-selective monoamine oxidase (MAO) inhibitor. It functions as a suicide inhibitor of mitochondrial MAO, forming a covalent adduct through a reactive phenylethyldiazene intermediate to cause irreversible enzymatic inactivation. In addition to MAO inhibition, phenelzine inhibits aromatic L-amino acid decarboxylase and tyrosine aminotransferase, thereby altering trace amine metabolic pathways in neural tissue. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 47 mg/mL (200.62 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 47 mg/mL
Ethanol 2 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.