PF-06821497 is a highly selective EZH2 inhibitor. It blocks PRC2 signaling by reducing H3K27me3, inhibiting cancer cell growth.
Comprehensive IC50 Values for PF-06821497 Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
PF-06821497 is a highly selective EZH2 inhibitor. It blocks PRC2 signaling by reducing H3K27me3, inhibiting cancer cell growth.