SMILES:
Cl.ClC1=C(N=CC=C1)N(C2CCCNC2)C(=O)C3=CC=C(C=C3)[N]4N=NC5=C4N=CC=C5
Chemical Structure
Check the
PF-06446846 hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-(3-chloro-2-pyridinyl)-N-[(3R)-piperidin-3-yl]-4-(triazolo[4,5-b]pyridin-3-yl)benzamide;hydrochloride | |
|---|---|---|
| CAS Number | 1632250-50-0 | |
| Molecular Formula |
C₂₂H₂₁Cl₂N₇O |
|
| Molecular Weight (MW) | 470.35 | |
| SMILES | Cl.ClC1=C(N=CC=C1)N(C2CCCNC2)C(=O)C3=CC=C(C=C3)[N]4N=NC5=C4N=CC=C5 | |
| InChIKey | AQSJYIVIWBIHOU-UNTBIKODSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
94 mg/mL
(199.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 94 mg/mL |
| Ethanol | 94 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- PF-06446846 hydrochloride Solubility in DMSO
- PF-06446846 hydrochloride Stock Solution
- PF-06446846 hydrochloride Storage
- PF-06446846 hydrochloride Stability
- PF-06446846 hydrochloride Molecular Weight
- PF-06446846 hydrochloride CAS Number
- PF-06446846 hydrochloride Chemical Structure (2D and 3D)
- PF-06446846 hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.