Molecular Weight: 400.38 g/mol
Chemical Structure
Check the
PF-04957325
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
80 mg/mL
(199.81 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Chemical Information
| IUPAC Name | 3-[[(2R)-4-(1,3-thiazol-2-ylmethyl)morpholin-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine | |
|---|---|---|
| CAS Number | 1305115-80-3 | |
| Molecular Formula |
C14H15F3N8OS |
|
| Molecular Weight (MW) | 400.38 | |
| InChIKey | VNLPYEMGHGDRRZ-MRVPVSSYSA-N |
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Note: Technical data last updated: Sep 1, 2026.