CAS No. 100299-08-9
| CAS Number | 100299-08-9 | |
|---|---|---|
| Molecular Formula |
C10H7N6O.K |
|
| Molecular Weight (MW) | 266.3 | |
| SMILES | CC1=CC=CN2C1=NC=C(C2=O)C3=NN=N[N-]3.[K+] |
Pemirolast potassium (BMY26517) is an antiallergic agent that functions as a histamine H1 receptor antagonist and mast cell stabilizer. It inhibits the antigen-induced release of inflammatory chemical mediators, such as histamine and leukotrienes, from mast cells and basophils. By suppressing mast cell degranulation, pemirolast potassium mitigates hypersensitivity responses and attenuates downstream inflammatory cascades associated with allergic reactions.
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Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| Water | 53 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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