Home Biosimilar Antibodies Metabolism PSMA Pelgifatamab (Anti-FOLH1 / PSMA)
For research use only. Not for use in humans.

Pelgifatamab (Anti-FOLH1 / PSMA)

Synonyms: FGFR-1， CD331

Pelgifatamab (anti-FOLH1 / PSMA) is an immunoglobulin G1-kappa monoclonal antibody targated against FOLH1 (folate hydrolase, prostate-specific membrane antigen, psma). MW: 146.24 KD.

Pelgifatamab (Anti-FOLH1 / PSMA)

Quality Control

Batch: A291201 Purity: 99% Protein concentration: 7.076mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Pelgifatamab (anti-FOLH1 / PSMA) is an immunoglobulin G1-kappa monoclonal antibody targated against FOLH1 (folate hydrolase, prostate-specific membrane antigen, psma). MW: 146.24 KD.

Product Details

CAS No. 2414550-93-7
Molecular Weight 146.24
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT07200830 RECRUITING Drug: Lutetium Lu 177 Vipivotide Tetraxetan Metastatic Castration-Resistant Prostate Carcinoma; Metastatic Prostate Adenocarcinoma; Stage IVB Prostate Cancer AJCC v8 Alliance for Clinical Trials in Oncology 2026-03-31 PHASE3
NCT06600802 RECRUITING Castration-resistant Metastatic Prostate Cancer; Treated by 177Lutetium-PSMA-617 (Lu-PSMA) Centre Jean Perrin 2024-10-08
NCT07426094 RECRUITING Drug: Androgen Deprivation Therapy (ADT)|Drug: Androgen Rece Prostate Cancer; Brachytherapy; Stereotactic Body Radiation Therapy (SBRT); Dose Escalation: Solid Tumors; Regionally Advanced Prostate Cancer Affidea Nu-med Center of Oncological DIagnostics and Therapy 2026-03-19 PHASE2; PHASE3
NCT07426055 RECRUITING Drug: Androgen Deprivation Therapy (ADT) Prostate Cancer (Adenocarcinoma); Prostate Brachytherapy; Stereotactic Body Radiation Therapy (SBRT); Dose Escalation: Solid Tumors; Localized Prostate Cancer Affidea Nu-med Center of Oncological DIagnostics and Therapy 2026-03-19 PHASE2; PHASE3
NCT07237269 RECRUITING Drug: Androgen Deprivation Therapy (ADT)|Drug: Abiraterone|D Prostate Cancer University of Nebraska 2026-10-15 PHASE2
NCT05896371 NOT_YET_RECRUITING Drug: 177Lu-PSMA-I&T - escalating renal absorbed dose|Drug: Cancer; Prostate Cancer; Metastatic Cancer; Metastatic Prostate Cancer CHU de Quebec-Universite Laval 2028-03 PHASE1; PHASE2

(data from https://clinicaltrials.gov, updated on 2026-09-02)

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