CAS No. 459836-30-7
Batch:
Purity:98.28
Chemical Structure
Check the
PEAQX
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 459836-30-7 | |
|---|---|---|
| Molecular Formula |
C17H17BrN3O5P |
|
| Molecular Weight (MW) | 454.21 | |
| SMILES | CC(NC(C1=C2NC(=O)C(=O)NC2=CC=C1)[P;v5](O)(O)=O)C3=CC=C(Br)C=C3 |
PEAQX (NVP-AAM is an orally bioavailable competitive N-methyl-D-aspartate (NMDA) receptor antagonist that demonstrates greater than 100-fold selectivity for human NMDA 1A/2A over 1A/2B subunit receptors. Targeted inhibition of GluN2A-containing receptors impairs glutamate-driven ionotropic signaling and synaptic neurotransmission pathways, thereby suppressing excitotoxic excitation and conferring strong protective anticonvulsant activity in electroshock-induced convulsion models. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
91 mg/mL
(200.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.