CAS No. 102625-70-7

Batch: Purity:99.94
Pantoprazole  Chemical Structure
Chemical Structure
Check the Pantoprazole product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 6-(difluoromethoxy)-2-[(3,4-dimethoxy-2-pyridinyl)methylsulfinyl]-1H-benzimidazole
CAS Number 102625-70-7
Molecular Formula

C16H15F2N3O4S

Molecular Weight (MW) 383.37
SMILES COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC
InChIKey IQPSEEYGBUAQFF-UHFFFAOYSA-N

Ordering Information

Biological Activity

Pantoprazole is a proton pump inhibitor that targets gastric H+/K+-ATPase in parietal cells. It irreversibly inhibits H+/K+-ATPase enzyme function to suppress gastric acid production. By accumulating in the acidic canaliculi of parietal cells, pantoprazole converts into an active sulfenamide intermediate that covalently binds to cysteine residues of the enzyme, leading to sustained inhibition of gastric acid secretion. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 76 mg/mL (198.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 76 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.