CAS No. 204255-11-8
Batch:
Purity:99.99
Chemical Structure
Check the
Oseltamivir Phosphate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate;phosphoric acid | |
|---|---|---|
| CAS Number | 204255-11-8 | |
| Molecular Formula |
C16H28N2O4.H3PO4 |
|
| Molecular Weight (MW) | 410.4 | |
| SMILES | CCC(CC)OC1C=C(CC(C1NC(=O)C)N)C(=O)OCC.OP(=O)(O)O | |
| InChIKey | PGZUMBJQJWIWGJ-ONAKXNSWSA-N |
Biological Activity
Oseltamivir phosphate is a prodrug that is hepatically converted into its active metabolite, oseltamivir carboxylate, a potent and selective inhibitor of influenza viral neuraminidase. By competitively targeting neuraminidase, it prevents the enzymatic cleavage of terminal sialic acid residues on host cell surfaces. This blockade impairs the release of newly formed viral particles from infected cells and suppresses viral replication and dissemination. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 82 mg/mL |
| Ethanol | Insoluble |
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 82 mg/mL |
| Ethanol | Insoluble |
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 82 mg/mL |
| Ethanol | Insoluble |
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 82 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Reference
Jump to
- Oseltamivir Phosphate Clinical Trials
- Oseltamivir Phosphate Solubility in DMSO
- Oseltamivir Phosphate Stock Solution
- Oseltamivir Phosphate Storage
- Oseltamivir Phosphate Stability
- Oseltamivir Phosphate Molecular Weight
- Oseltamivir Phosphate SMILES
- Oseltamivir Phosphate Chemical Structure (2D and 3D)
- Oseltamivir Phosphate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.