CAS No. 204255-11-8
| IUPAC Name | ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate;phosphoric acid | |
|---|---|---|
| CAS Number | 204255-11-8 | |
| Molecular Formula |
C16H28N2O4.H3PO4 |
|
| Molecular Weight (MW) | 410.4 | |
| SMILES | CCC(CC)OC1C=C(CC(C1NC(=O)C)N)C(=O)OCC.OP(=O)(O)O | |
| InChIKey | PGZUMBJQJWIWGJ-ONAKXNSWSA-N |
Oseltamivir phosphate is a prodrug that is hepatically converted into its active metabolite, oseltamivir carboxylate, a potent and selective inhibitor of influenza viral neuraminidase. By competitively targeting neuraminidase, it prevents the enzymatic cleavage of terminal sialic acid residues on host cell surfaces. This blockade impairs the release of newly formed viral particles from infected cells and suppresses viral replication and dissemination. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 82 mg/mL |
| Ethanol | Insoluble |
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 82 mg/mL |
| Ethanol | Insoluble |
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 82 mg/mL |
| Ethanol | Insoluble |
| DMSO |
82 mg/mL
(199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 82 mg/mL |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
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