Onvansertib is a potent and highly specific PLK1 inhibitor. It affects PI3K/AKT/mTOR, hypoxia, and DNA repair signaling pathways by inducing G2/M mitotic arrest and chromosomal abnormalities, thereby inhibiting cancer cell proliferation and promoting apoptosis.
Onvansertib (NMS-1286937, NMS-P937) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Onvansertib (NMS-1286937, NMS-P937) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
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- Onvansertib (NMS-1286937, NMS-P937) Mechanism of Action: PLK1 Inhibition in Colorectal Cancer Cell Research
- Onvansertib (NMS-1286937, NMS-P937) Clinical Trials
- Onvansertib (NMS-1286937, NMS-P937): Selectivity & Specificity
- Onvansertib (NMS-1286937, NMS-P937) Working Concentration | Cell Culture | Treatment
- Onvansertib (NMS-1286937, NMS-P937) Solubility in DMSO
- Onvansertib (NMS-1286937, NMS-P937) Stock Solution
- Onvansertib (NMS-1286937, NMS-P937) Storage
- Onvansertib (NMS-1286937, NMS-P937) Stability
- Onvansertib (NMS-1286937, NMS-P937) Combination Database
- Onvansertib (NMS-1286937, NMS-P937) Molecular Weight
- Onvansertib (NMS-1286937, NMS-P937) SMILES
- Onvansertib (NMS-1286937, NMS-P937) CAS Number
- Onvansertib (NMS-1286937, NMS-P937) Chemical Structure (2D and 3D)
- Onvansertib (NMS-1286937, NMS-P937) Sigma (ADVH99C0EDE4)? Try a better option.
- Onvansertib (NMS-1286937, NMS-P937) Cayman (28762)? Try a better option.
- Onvansertib (NMS-1286937, NMS-P937) MedChemExpress (HY-15828)? Try a better option.
- Onvansertib (NMS-1286937, NMS-P937) APExBIO (B4094)? Try a better option.
- Onvansertib (NMS-1286937, NMS-P937) SDS｜MSDS