For research use only. Not for use in humans.

Omburtamab (Anti-B7-H3 / CD276)

Synonyms: null Cat.No.A2986 Purity:99%

Omburtamab (Anti-B7-H3 / CD276) is a monoclonal antibody targeting CD276 (also known as B7-H3). It can bind tumor tissues and be used in various cancers research like non-small cell lung cancer (NSCLC). MW :145.04 KD.

1 Citation

17 Nobel Prize winners have used Selleck products

Shimon Sakaguchi

Nature Communications 2025,16, Article number:1325

David Baker

Dev Cell 2023, 58(20):2163-2180.e9.

David Julius

Cell 2017, 185-198.e16

Michael Houghton

Cell Chem Biol, 2020, 27(7):780-792.e5

Charles M. Rice

Cell 2018, 172(3):423-438.e25

Quality Control

Batch: A298601 Purity: 99% Protein concentration: 8.3mg/ml Endotoxin Level: ＜1EU/mg

Cited in Nature Medicine for its top-tier quality
COA
SDS
Datasheet

Specificity

Name	Citation	CD38	CD45	CD39	CD88	CD73	Others
RBN013209	0	++
MK-0159	0	+++
CD38 inhibitor 1 (compound 78c)	7	+++
AB680	0					++++
NQ301	1		+				TXA2 receptor
SodiuM Metatungstate	3			++
PMX-53	3				✔
LY-3475070	2					✔

Expand to Check More

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Omburtamab (Anti-B7-H3 / CD276) is a monoclonal antibody targeting CD276 (also known as B7-H3). It can bind tumor tissues and be used in various cancers research like non-small cell lung cancer (NSCLC). MW :145.04 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/33514401/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1895083-75-6
Molecular Weight	145.04
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.