CAS No. 1258226-87-7
Batch:
Purity:99.77
Chemical Structure
Check the
Ombitasvir (ABT-267)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | methyl N-[(2S)-1-[(2S)-2-[[4-[(2S,5S)-1-(4-tert-butylphenyl)-5-[4-[[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]phenyl]pyrrolidin-2-yl]phenyl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate | |
|---|---|---|
| CAS Number | 1258226-87-7 | |
| Molecular Formula |
C50H67N7O8 |
|
| Molecular Weight (MW) | 894.11 | |
| SMILES | CC(C)C(C(=O)N1CCCC1C(=O)NC2=CC=C(C=C2)C3CCC(N3C4=CC=C(C=C4)C(C)(C)C)C5=CC=C(C=C5)NC(=O)C6CCCN6C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC | |
| InChIKey | PIDFDZJZLOTZTM-KHVQSSSXSA-N |
Ombitasvir (ABT-267) is a potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A) with broad antiviral activity. By targeting HCV NS5A, ombitasvir disrupts viral RNA replication and virion assembly across multiple HCV genotypes. Inhibition of this essential viral protein impairs viral replication complex formation and suppresses viral propagation, leading to reduced viral load in cellular models. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(111.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Ombitasvir (ABT-267) Clinical Trials
- Ombitasvir (ABT-267) Solubility in DMSO
- Ombitasvir (ABT-267) Stock Solution
- Ombitasvir (ABT-267) Storage
- Ombitasvir (ABT-267) Stability
- Ombitasvir (ABT-267) Molecular Weight
- Ombitasvir (ABT-267) SMILES
- Ombitasvir (ABT-267) Chemical Structure (2D and 3D)
- Ombitasvir (ABT-267) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.