CAS No. 868049-49-4
Batch:
Purity:99.44
Chemical Structure
Check the
Olodaterol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 868049-49-4 | |
|---|---|---|
| Molecular Formula |
C21H26N2O5 |
|
| Molecular Weight (MW) | 386.44 | |
| SMILES | COC1=CC=C(CC(C)(C)NCC(O)C2=C3OCC(=O)NC3=CC(=C2)O)C=C1 |
Olodaterol is a potent, long-acting β2-adrenergic receptor agonist. Activation of the β2-adrenergic receptor stimulates intracellular adenylate cyclase, leading to increased cyclic AMP levels and activation of protein kinase A. This signaling cascade results in airway smooth muscle relaxation and bronchodilation. Olodaterol exhibits high selectivity and sustained bronchodilatory activity, making it effective for the management of respiratory diseases such as chronic obstructive pulmonary disease. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
77 mg/mL
(199.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 40 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.