CAS No. 112-80-1

Batch: Purity:99.85
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Oleic acid (cis-9-Octadecenoic acid) Chemical Structure
Chemical Structure
Check the Oleic acid (cis-9-Octadecenoic acid) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 112-80-1
Molecular Formula

C18H34O2
Molecular Weight (MW) 282.46

Ordering Information

Biological Activity

Oleic acid is an abundant monounsaturated fatty acid that functions as an endogenous agonist of free fatty acid receptor 1 (FFAR1/GPR40) and activates peroxisome proliferator-activated receptors (PPARs). Activation of GPR40 by oleic acid triggers intracellular calcium mobilization, influencing lipid sensing, insulin secretion, and metabolic homeostasis. Additionally, oleic acid modulates Na+/K+-ATPase activity and serves as an inducer in animal models of renal failure and acute tissue injury. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Ethanol 100 mg/mL
DMSO 50 mg/mL (177.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.