Molecular Weight: 434.46 g/mol
Chemical Structure
Check the
AZD2281 (Olaparib)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
125 mg/mL
(287.71 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
87 mg/mL
(200.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
43 mg/mL
(98.97 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
86 mg/mL
(197.94 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
87 mg/mL
(200.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| IUPAC Name | 4-[[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one | |
|---|---|---|
| CAS Number | 763113-22-0 | |
| Molecular Formula |
C24H23FN4O3 |
|
| Molecular Weight (MW) | 434.46 | |
| SMILES | C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F | |
| InChIKey | FDLYAMZZIXQODN-UHFFFAOYSA-N |
- AZD2281 (Olaparib) Mechanism of Action: PARP Inhibition in Homologous Recombination Deficient Cell Research
- AZD2281 (Olaparib) Clinical Trials
- AZD2281 (Olaparib): Selectivity & Specificity
- AZD2281 (Olaparib) Working Concentration | Cell Culture | Treatment
- AZD2281 (Olaparib) Solubility in DMSO
- AZD2281 (Olaparib) Stock Solution
- AZD2281 (Olaparib) Storage
- AZD2281 (Olaparib) Stability
- AZD2281 (Olaparib) Combination Database
- AZD2281 (Olaparib) SMILES
- AZD2281 (Olaparib) CAS Number
- AZD2281 (Olaparib) Chemical Structure (2D and 3D)
- AZD2281 (Olaparib) IC50 for Cell-based and Cell-free Assays
- AZD2281 (Olaparib) Sigma (SML3705)? Try a better option.
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- AZD2281 (Olaparib) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.