AZD2281 is a potent, selective PARP inhibitor. It affects DDR signaling by trapping PARP on DNA, inducing synthetic lethality.
Comprehensive IC50 Values for AZD2281 (Olaparib) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
AZD2281 is a potent, selective PARP inhibitor. It affects DDR signaling by trapping PARP on DNA, inducing synthetic lethality.