CAS No. 70775-75-6

Batch: Purity:99.88
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Octenidine Dihydrochloride Chemical Structure
Chemical Structure
Check the Octenidine Dihydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-octyl-1-[10-(4-octylimino-1-pyridinyl)decyl]pyridin-4-imine;dihydrochloride
CAS Number 70775-75-6
Molecular Formula

C36H62N4.2HCl
Molecular Weight (MW) 623.83
SMILES Cl.Cl.CCCCCCCCN=C1C=CN(CCCCCCCCCCN2C=CC(C=C2)=NCCCCCCCC)C=C1
InChIKey SMGTYJPMKXNQFY-UHFFFAOYSA-N

Ordering Information

Biological Activity

Octenidine dihydrochloride is a cationic bispyridine surfactant with broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria. It targets microbial cell membranes, leading to rapid membrane disruption, leakage of cytoplasmic contents, and cell lysis. This membrane-targeting mechanism suppresses bacterial cell viability and maintains potent bactericidal efficacy across a wide range of bacterial strains. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 60 mg/mL (96.18 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.