CAS No. 300586-90-7
Batch:
Purity:99.21
Chemical Structure
Check the
OAC1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide | |
|---|---|---|
| CAS Number | 300586-90-7 | |
| Molecular Formula |
C14H11N3O |
|
| Molecular Weight (MW) | 237.26 | |
| SMILES | C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3 | |
| InChIKey | HWJRIFZDXJKJJN-UHFFFAOYSA-N |
Biological Activity
OAC1 is a small-molecule reprogramming enhancer that activates the promoter-driven transcription of Oct4 and Nanog. By enhancing the transcriptional activity of core pluripotency factors Oct4 and Nanog, OAC1 accelerates somatic cell reprogramming into induced pluripotent stem cells (iPSCs). This compound facilitates the transition to a pluripotent state by boosting pluripotency gene networks and improving overall reprogramming efficiency in cell-based models.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
47 mg/mL
(198.09 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 21 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
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Note: Technical data last updated: Sep 1, 2026.