CAS No. 1476-53-5
Batch:
Purity:98.89
Chemical Structure
Check the
Novobiocin Sodium (Cathomycin, Albamycin)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | sodium 7-[(2R,3R,4S,5R)-4-carbamoyloxy-3-hydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy-3-[[4-hydroxy-3-(3-methylbut-2-enyl)benzoyl]amino]-8-methyl-2-oxochromen-4-olate | |
|---|---|---|
| CAS Number | 1476-53-5 | |
| Molecular Formula |
C31H35N2O11.Na |
|
| Molecular Weight (MW) | 634.61 | |
| SMILES | CC1=C(C=CC2=C1OC(=O)C(=C2O)NC(=O)C3=CC(=C(C=C3)[O-])CC=C(C)C)OC4C(C(C(C(O4)(C)C)OC)OC(=O)N)O.[Na+] | |
| InChIKey | WWPRGAYLRGSOSU-RNROJPEYSA-M |
Novobiocin Sodium is an aminocoumarin antibiotic that acts as a competitive inhibitor of bacterial DNA gyrase by targeting the GyrB subunit ATP-binding site, and also binds the C-terminal domain of heat shock protein 90 (Hsp90). By blocking ATPase activity, it inhibits bacterial DNA supercoiling and replication, while Hsp90 inhibition promotes the degradation of client proteins and suppresses cellular survival pathways. [1]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(157.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
100 mg/mL
(157.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
100 mg/mL
(157.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
100 mg/mL
(157.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
100 mg/mL
(157.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Novobiocin Sodium (Cathomycin, Albamycin) Clinical Trials
- Novobiocin Sodium (Cathomycin, Albamycin) Solubility in DMSO
- Novobiocin Sodium (Cathomycin, Albamycin) Stock Solution
- Novobiocin Sodium (Cathomycin, Albamycin) Storage
- Novobiocin Sodium (Cathomycin, Albamycin) Stability
- Novobiocin Sodium (Cathomycin, Albamycin) Molecular Weight
- Novobiocin Sodium (Cathomycin, Albamycin) SMILES
- Novobiocin Sodium (Cathomycin, Albamycin) Chemical Structure (2D and 3D)
- Novobiocin Sodium (Cathomycin, Albamycin) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.