CAS No. 51-98-9
Batch:
Purity:99.50
Chemical Structure
Check the
Norethindrone acetate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 51-98-9 | |
|---|---|---|
| Molecular Formula |
C22H28O3 |
|
| Molecular Weight (MW) | 340.46 | |
| SMILES | CC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4C3CCC12C)C#C |
Norethindrone acetate is a synthetic progestin that functions as a potent progesterone receptor agonist. Upon binding to progesterone receptors, it modulates transcriptional activity, regulating gonadotropin secretion and downstream reproductive hormone signaling pathways. Through these targeted hormonal actions, it exerts profound progestational effects that inhibit ovulation and alter endometrial physiology. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
68 mg/mL
(199.72 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 68 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Norethindrone acetate Clinical Trials
- Norethindrone acetate Solubility in DMSO
- Norethindrone acetate Stock Solution
- Norethindrone acetate Storage
- Norethindrone acetate Stability
- Norethindrone acetate Molecular Weight
- Norethindrone acetate SMILES
- Norethindrone acetate Chemical Structure (2D and 3D)
- Norethindrone acetate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.