For research use only. Not for use in humans.

Nimacimab (Anti-CB1 / CNR1)

Synonyms: RYI-018 Cat.No.A2574 Purity:99%

Nimacimab (Anti-CB1/CNR1) is a negative-allosteric modulating monoclonal antibody targeting CB1 receptor. Nimacimab can be used for research of metabolic diseases. MW:145.5 KD.

Quality Control

Batch: A257401 Purity: 99% Protein concentration: 4.19mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Specificity

Name	Citation	CB1	CB2
Otenabant (CP-945598) HCl	2	++++
RTICBM-189	0	++
JD-5037	0	+++
6-Iodopravadoline (AM630)	2		++
AM251	12	✔
Pregnenolone monosulfate sodium	0	✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Nimacimab (Anti-CB1/CNR1) is a negative-allosteric modulating monoclonal antibody targeting CB1 receptor. Nimacimab can be used for research of metabolic diseases. MW:145.5 KD.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2098636-09-8
Molecular Weight	145.5 kDa
Isotype	Human IgG4SP
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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