For research use only. Not for use in humans.

Nesvacumab (Anti-ANGPT2)

Synonyms: REGN910 Cat.No.A2624 Purity:99%

Nesvacumab (Anti-ANGPT2) is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically targets the Tie2 receptor ligand Angiopoietin-2 (Ang2). It has potential antitumor activity. MW :150 KD.

Quality Control

Batch: Purity: 99% Protein concentration: 5.029mg/ml Endotoxin Level: ＜1EU/mg

Mechanism of Action

Description	Nesvacumab (Anti-ANGPT2) is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically targets the Tie2 receptor ligand Angiopoietin-2 (Ang2). It has potential antitumor activity. MW :150 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/26490310/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1296818-77-3
Molecular Weight	144.86
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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