Molecular Weight: 354.36 g/mol
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Chemical Structure
Check the
Nesolicaftor (PTI-428)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
71 mg/mL
(200.36 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| CAS Number | 1953130-87-4 | |
|---|---|---|
| Molecular Formula |
C18H18N4O4 |
|
| Molecular Weight (MW) | 354.36 |
- Nesolicaftor (PTI-428) Clinical Trials
- Nesolicaftor (PTI-428) Solubility in DMSO
- Nesolicaftor (PTI-428) Stock Solution
- Nesolicaftor (PTI-428) Storage
- Nesolicaftor (PTI-428) Stability
- Nesolicaftor (PTI-428) CAS Number
- Nesolicaftor (PTI-428) Chemical Structure (2D and 3D)
- Nesolicaftor (PTI-428) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.