CAS No. 970-74-1

Batch: Purity:99.38
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(-)-epigallocatechin Chemical Structure
Chemical Structure
Check the (-)-epigallocatechin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2R,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
CAS Number 970-74-1
Molecular Formula

C15H14O7
Molecular Weight (MW) 306.27
SMILES C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O
InChIKey XMOCLSLCDHWDHP-IUODEOHRSA-N

Ordering Information

Biological Activity

(-)-Epigallocatechin is a natural polyphenolic flavonoid abundant in green tea plants that exhibits broad anti-tumor, anti-cancer, and anti-inflammatory activities. It modulates critical cellular signaling cascades, including the NF-kB and MAPK signaling pathways, thereby suppressing cancer cell proliferation, promoting apoptotic cell death, and reducing the expression of pro-inflammatory cytokine mediators in various in vitro cellular models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 61 mg/mL (199.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.