Nedisertib (M3814) SMILES

SMILES:

COC1=NN=C(C=C1)C(C2=C(C=C(C(=C2)C3=NC=NC4=C3C=CC(=C4)N5CCOCC5)F)Cl)O

Chemical Structure

Check the Nedisertib (M3814) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

IUPAC Name	(S)-[2-chloro-4-fluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol
CAS Number	1637542-33-6
Molecular Formula	C₂₄H₂₁ClFN₅O₃
Molecular Weight (MW)	481.91
SMILES	COC1=NN=C(C=C1)C(C2=C(C=C(C(=C2)C3=NC=NC4=C3C=CC(=C4)N5CCOCC5)F)Cl)O
InChIKey	MOWXJLUYGFNTAL-DEOSSOPVSA-N

Concentration Volume Mass

Batch:

All in vitro solubility values are batch-tested experimental data (non-literature values).

Solvent	Solubility & Note
DMSO	96 mg/mL (199.2 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water	Insoluble
Ethanol	Insoluble
DMSO	96 mg/mL (199.2 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol	3 mg/mL
Water	Insoluble
DMSO	96 mg/mL (199.2 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol	2 mg/mL
Water	Insoluble
DMSO	48 mg/mL (99.6 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water	Insoluble
Ethanol	Insoluble
DMSO	96 mg/mL (199.2 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol	8 mg/mL
Water	Insoluble

FAQ

Q: Why does a DMSO stock precipitate in media/saline?

A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.

How to fix it?