Molecular Weight: 562.71 g/mol
Chemical Structure
Check the
Naquotinib(ASP8273)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Ethanol | 100 mg/mL |
| DMSO |
52 mg/mL
(92.4 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | 6-ethyl-3-[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxypyrazine-2-carboxamide | |
|---|---|---|
| CAS Number | 1448232-80-1 | |
| Molecular Formula |
C30H42N8O3 |
|
| Molecular Weight (MW) | 562.71 | |
| SMILES | CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC5CCN(C5)C(=O)C=C | |
| InChIKey | QKDCLUARMDUUKN-XMMPIXPASA-N |
- Naquotinib(ASP8273) Clinical Trials
- Naquotinib(ASP8273) Solubility in DMSO
- Naquotinib(ASP8273) Stock Solution
- Naquotinib(ASP8273) Storage
- Naquotinib(ASP8273) Stability
- Naquotinib(ASP8273) SMILES
- Naquotinib(ASP8273) CAS Number
- Naquotinib(ASP8273) Chemical Structure (2D and 3D)
- Naquotinib(ASP8273) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.