CAS No. 7772-94-3
Batch:
Purity:99.84
Chemical Structure
Check the
N-Acetyl-D-mannosamine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 7772-94-3 | |
|---|---|---|
| Molecular Formula |
C8H15NO6 |
|
| Molecular Weight (MW) | 221.21 | |
| SMILES | CC(=O)NC1C(O)OC(CO)C(O)C1O |
N-Acetyl-D-mannosamine (ManNAc) is an essential precursor in the sialic acid biosynthetic pathway. By promoting sialic acid biosynthesis, ManNAc restores cellular sialylation, which plays a key role in neuronal membrane function and synaptic plasticity. Consequently, ManNAc treatment alleviates age-dependent attenuation of synaptic transmission and long-term potentiation (LTP), offering therapeutic potential for cognitive dysfunction. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
44 mg/mL
(198.9 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 44 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- N-Acetyl-D-mannosamine Clinical Trials
- N-Acetyl-D-mannosamine Solubility in DMSO
- N-Acetyl-D-mannosamine Stock Solution
- N-Acetyl-D-mannosamine Storage
- N-Acetyl-D-mannosamine Stability
- N-Acetyl-D-mannosamine Molecular Weight
- N-Acetyl-D-mannosamine SMILES
- N-Acetyl-D-mannosamine Chemical Structure (2D and 3D)
- N-Acetyl-D-mannosamine SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.