MRTX1133 is a potent, selective, noncovalent KRAS G12D inhibitor. It affects KRAS/MAPK and PI3K/AKT signaling pathways by binding to the KRAS G12D protein, effectively inhibiting tumor cell proliferation, migration, and growth.
MRTX1133 IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for MRTX1133 Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.