Molecular Weight: 373.45 g/mol
Chemical Structure
Check the
Motesanib (AMG-706)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
18.2 mg/mL
(48.73 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 8 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide | |
|---|---|---|
| CAS Number | 453562-69-1 | |
| Molecular Formula |
C22H23N5O |
|
| Molecular Weight (MW) | 373.45 | |
| SMILES | CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C | |
| InChIKey | RAHBGWKEPAQNFF-UHFFFAOYSA-N |
- Motesanib (AMG-706) Clinical Trials
- Motesanib (AMG-706) Solubility in DMSO
- Motesanib (AMG-706) Stock Solution
- Motesanib (AMG-706) Storage
- Motesanib (AMG-706) Stability
- Motesanib (AMG-706) SMILES
- Motesanib (AMG-706) CAS Number
- Motesanib (AMG-706) Chemical Structure (2D and 3D)
- Motesanib (AMG-706) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.