CAS No. 219315-22-7

Batch: Purity:99.93
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Mitochondrial Fusion Promoter M1 Chemical Structure
Chemical Structure
Check the Mitochondrial Fusion Promoter M1 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-chloro-2-[(E)-C-methyl-N-(2,4,6-trichloroanilino)carbonimidoyl]phenol
CAS Number 219315-22-7
Molecular Formula

C14H10Cl4N2O
Molecular Weight (MW) 364.05
SMILES CC(=N/NC1=C(Cl)C=C(Cl)C=C1Cl)\C2=C(O)C=CC(=C2)Cl
InChIKey CYVDGZYJHHYIIU-FBCYGCLPSA-N

Ordering Information

Biological Activity

Mitochondrial fusion promoter M1 is a small-molecule mitochondrial dynamic modulator that targets mitochondrial fusion pathways. It increases the expression of mitofusin 2 (Mfn2), a mitochondrial outer membrane fusion protein, thereby promoting mitochondrial elongation and preserving cellular respiration. Through these mechanisms, M1 reduces mitochondrial dysfunction, maintains organelle integrity, and alleviates tissue injury in rat models of cardiac ischemia/reperfusion injury. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 73 mg/mL (200.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.