CAS No. 208538-73-2

Batch: Purity:99.46
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Micafungin Sodium (FK-463) Chemical Structure
Chemical Structure
Check the Micafungin Sodium (FK-463) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 208538-73-2
Molecular Formula

C56H70N9NaO23S
Molecular Weight (MW) 1292.26
SMILES CCCCCOC1=CC=C(C=C1)C2=CC(=NO2)C3=CC=C(C=C3)C(=O)NC4CC(C(NC(=O)C5C(C(CN5C(=O)C(NC(=O)C(NC(=O)C6CC(CN6C(=O)C(NC4=O)C(C)O)O)C(C(C7=CC(=C(C=C7)O)OS(=O)(=O)[O-])O)O)C(CC(=O)N)O)C)O)O)O.[Na+]

Ordering Information

Biological Activity

Micafungin Sodium (FK-463) is an echinocandin antifungal compound that acts as a selective inhibitor of 1,3-beta-D-glucan synthase. By blocking the synthesis of 1,3-beta-D-glucan, a critical structural polymer in the fungal cell wall, it compromises structural wall integrity. This inhibition impairs cell wall assembly, resulting in osmotic instability, severe cell wall deformation, and subsequent fungal cell lysis.

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (77.38 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.