Melphalan has been evaluated in numerous clinical trials spanning Phase I through Phase IV across diverse oncological and hematological indications, including multiple myeloma, plasma cell disorders, leukemia, retinoblastoma, and myeloablative conditioning for stem cell transplantation. Sponsored by academic medical centers, pediatric research hospitals, and pharmaceutical companies, these protocols represent active, recruiting, completed, terminated, and withdrawn recruitment statuses.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT06986382 | NOT_YET_RECRUITING | Crohn Disease |
Stanford University |
2025-07 | PHASE1; PHASE2 |
| NCT04681417 | RECRUITING | Retinoblastoma |
Institut Curie |
2021-03-25 | PHASE2; PHASE3 |
| NCT03852407 | RECRUITING | Acute Myeloid Leukemia in Remission; Myelodysplastic Syndromes; Chronic Myeloid Leukemia in Remission; Myeloproliferative Syndrome; Myeloproliferative Disorder; Acute Lymphoid Leukemia in Remission; Multiple Myeloma; Chronic Lymphoid Leukemia; Non Hodgkin Lymphoma; Hodgkin Lymphoma |
University of Liege |
2019-02-04 | PHASE2 |
| NCT07624513 | NOT_YET_RECRUITING | Multiple Myeloma |
Dana-Farber Cancer Institute |
2026-06-08 | PHASE3 |
| NCT05565105 | NOT_YET_RECRUITING | Leukemia, Myeloid, Acute; Leukemia, Lymphocytic, Acute |
Guenther Koehne |
2026-06 | PHASE2 |
| NCT05617625 | SUSPENDED | Myelodysplastic Syndromes; Graft Vs Host Disease; Graft-versus-host-disease |
Guenther Koehne |
2026-06 | PHASE2 |
| NCT05508009 | RECRUITING | SIOD; Cystinosis; FSGS; SLE Nephritis; CKD Stage 4 |
Alice Bertaina |
2023-01-10 | PHASE1; PHASE2 |
| NCT07257419 | RECRUITING | Relapsed Pediatric ALL; Hematopoietic Cell Transplantation; Hematologic Malignancy |
St. Jude Children's Research Hospital |
2026-10-03 | PHASE1 |
| NCT04982354 | WITHDRAWN | Acute Myeloid Leukemia |
Guenther Koehne |
2022-07-05 | PHASE1; PHASE2 |
| NCT07276386 | RECRUITING | Metastatic Uveal Melanoma |
H. Lee Moffitt Cancer Center and Research Institute |
2025-12-31 | PHASE2 |
| NCT07281924 | RECRUITING | Metastatic Melanoma; Liver Metastases |
University of Wisconsin, Madison |
2026-09 | PHASE1; PHASE2 |
| NCT07228624 | RECRUITING | Myelodysplastic/Myeloproliferative Neoplasm; Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2026-02-04 | PHASE2 |
| NCT06022939 | RECRUITING | AL Amyloidosis |
SWOG Cancer Research Network |
2024-07-01 | PHASE3 |
| NCT06195891 | RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome |
City of Hope Medical Center |
2024-05-24 | PHASE1 |
| NCT07396480 | RECRUITING | Venentoclax; Myeloid Malignancies; Conditioning; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; Acute Myeloid Leucemia; Myeldysplastic Syndrome (MDS) |
First Affiliated Hospital of Zhejiang University |
2026-03-01 | PHASE3 |
| NCT06172296 | RECRUITING | Ganglioneuroblastoma, Nodular; Neuroblastoma |
National Cancer Institute (NCI) |
2024-04-19 | PHASE3 |
| NCT05477589 | RECRUITING | Acute Myeloid Leukemia (AML) in Remission; Stem Cell Transplantation |
Vastra Gotaland Region |
2022-06-07 | PHASE3 |
| NCT07644481 | NOT_YET_RECRUITING | AML (Acute Myelogenous Leukemia); Allogeneic Hematopoietic Stem Cell Transplantation Recipient |
Institute of Hematology & Blood Diseases Hospital, China |
2026-07-20 | |
| NCT07259161 | NOT_YET_RECRUITING | CML,Blast Phase; HSCT |
Institute of Hematology & Blood Diseases Hospital, China |
2025-12-15 | PHASE2 |
| NCT07582172 | RECRUITING | Acute Myeloid Leukemia With Complex Karyotype; Myelodysplastic Chronic Myelomonocytic Leukemia; Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Myelodysplastic Chronic Myelomonocytic Leukemia; Recurrent Myelodysplastic Syndrome; Recurrent Secondary Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia; Refractory Myelodysplastic Chronic Myelomonocytic Leukemia; Refractory Myelodysplastic Syndrome; Refractory Secondary Acute Myeloid Leukemia |
City of Hope Medical Center |
2027-04-05 | PHASE2 |
| NCT07052370 | RECRUITING | Hematologic Malignancy |
St. Jude Children's Research Hospital |
2025-09-25 | PHASE1 |
| NCT04150042 | RECRUITING | Pancreatic Adenocarcinoma Metastatic; BRCA1 Mutation; BRCA2 Mutation; Pancreatic Acinar Cell Carcinoma; Pancreatic Ductal Adenocarcinoma; Pancreatic Cancer; Metastatic Pancreatic Cancer; Metastatic Pancreatic Ductal Adenocarcinoma; Breast Cancer Metastatic; Breast Cancer Stage IV; Pancreatic Cancer Stage IV; HER2-negative Breast Cancer; HER2 Negative Breast Carcinoma; Adenocarcinoma of the Breast; PALB2 Gene Mutation; Pancreas Cancer, Metastatic; Pancreas Cancer, Recurrent; Pancreas Cancer; Stage IV Pancreatic Cancer; Stage 4 Pancreatic Cancer |
General Oncology, Inc. |
2021-01-13 | PHASE1 |
| NCT06133556 | NOT_YET_RECRUITING | Acute Myeloid Leukemia |
Institute of Hematology & Blood Diseases Hospital, China |
2023-11-24 | PHASE2 |
| NCT06815003 | RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Chronic Myelomonocytic Leukemia; Graft Versus Host Disease; Myelodysplastic Syndrome; Myeloproliferative Neoplasm |
City of Hope Medical Center |
2025-04-18 | PHASE2 |
| NCT07735637 | NOT_YET_RECRUITING | Newly Diagnosed Multiple Myeloma (NDMM) |
AstraZeneca |
2026-08-25 | PHASE3 |
| NCT06158828 | RECRUITING | AML, Childhood; Aml; Acute Myeloid Leukemia, Pediatric; Acute Myeloid Leukemia |
Washington University School of Medicine |
2024-11-15 | PHASE1; PHASE2 |
| NCT04678401 | RECRUITING | Stem Cell Transplant Complications; Graft Vs Host Disease; Myeloid Leukemia, Acute; Myeloid Leukemia in Relapse (Disorder); Myelodysplastic Syndromes |
Dana-Farber Cancer Institute |
2021-01-12 | PHASE1 |
| NCT06287944 | RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome |
City of Hope Medical Center |
2025-07-01 | PHASE1 |
| NCT06954987 | NOT_YET_RECRUITING | Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2026-07-17 | PHASE2 |
| NCT04903678 | RECRUITING | Retinoblastoma, Extraocular |
Eye & ENT Hospital of Fudan University |
2021-05-01 | |
| NCT07085156 | NOT_YET_RECRUITING | MDS |
Ruijin Hospital |
2025-08-01 | PHASE2 |
| NCT05088356 | ACTIVE_NOT_RECRUITING | Allogeneic Hematopoietic Cell Transplantation (HCT); Advanced Hematologic Malignancies; Acute Leukemia; Chronic Myelogenous Leukemia; Myelodysplastic Syndromes; Myeloproliferative Disorders |
Stanford University |
2021-09-07 | PHASE1 |
| NCT05504291 | RECRUITING | Bilateral Retinoblastoma; Childhood Intraocular Retinoblastoma; Group D Retinoblastoma; Stage I Retinoblastoma; Unilateral Retinoblastoma |
Children's Oncology Group |
2022-11-04 | PHASE2 |
| NCT03850366 | RECRUITING | Hematological Malignancy |
Henry Ford Health System |
2016-03-08 | PHASE2 |
| NCT07078721 | NOT_YET_RECRUITING | Aplastic Anemia Idiopathic |
Institute of Hematology & Blood Diseases Hospital, China |
2025-07-20 | PHASE2 |
| NCT05636787 | RECRUITING | Multiple Myeloma |
Insel Gruppe AG, University Hospital Bern |
2023-06-06 | PHASE2 |
| NCT04232085 | RECRUITING | Primary Immune Deficiency Disorder; Immune Deficiency Disease; Bone Marrow Failure; Short Telomere Length; Fanconi Anemia; Non Fanconi DNA-DSB Repair Disorder; Hoyeraal-Hreidarsson Syndrome; Dyskeratosis Congenita; Telomere Biology Disorder; Short Telomere Syndrome |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2020-02-12 | PHASE2 |
| NCT00871013 | ACTIVE_NOT_RECRUITING | Myeloma |
University of Arkansas |
2009-03 | PHASE2 |
| NCT05735717 | RECRUITING | Hematologic Malignancy; Acute Leukemia; Remission; Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia; AML; TP53; Intrachromosomal Amplification of Chromosome 21; Cytogenetic Abnormality; CNS Leukemia; Minimal Residual Disease; Myelodysplasia; Juvenile Myelomonocytic Leukemia; Somatic Mutation; PTPN11 Gene Mutation; N-RAS Gene Amplification; Neurofibromatosis 1; NF1 Mutation; CBL Gene Mutation; Monosomy 7; Chromosome Abnormality; Fetal Hemoglobin; Lymphoblastic Lymphoma; High Grade Non-Hodgkin's Lymphoma, Adult |
Masonic Cancer Center, University of Minnesota |
2023-05-11 | PHASE2 |
| NCT06679829 | RECRUITING | Multiple Myeloma |
Memorial Sloan Kettering Cancer Center |
2024-11-06 | PHASE2 |
| NCT06692452 | WITHDRAWN | Lymphoma; Peripheral T Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Enteropathy-Associated T-Cell Lymphoma; Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma |
Eric Jacobsen, MD |
2024-12-24 | PHASE2 |
| NCT06613035 | NOT_YET_RECRUITING | Acute Myeloid Leukemia |
Institute of Hematology & Blood Diseases Hospital, China |
2024-09-30 | PHASE3 |
| NCT05540340 | ACTIVE_NOT_RECRUITING | Lymphoma; Lymphoma, B-Cell; Lymphoma, T-Cell; Lymphoma, Hodgkin; Lymphoma, Non-Hodgkin |
Memorial Sloan Kettering Cancer Center |
2022-09-09 | PHASE1 |
| NCT06523699 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
Washington University School of Medicine |
2025-04-04 | PHASE1 |
| NCT00572169 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
University of Arkansas |
2006-11 | PHASE3 |
| NCT04022239 | RECRUITING | Hematopoietic and Lymphoid System Neoplasm |
M.D. Anderson Cancer Center |
2020-03-13 | PHASE1; PHASE2 |
| NCT04483206 | RECRUITING | Multiple Myeloma |
Emory University |
2021-05-20 | PHASE1 |
| NCT05436418 | RECRUITING | Peripheral Blood Stem Cell Transplantation; Hematopoietic Stem Cell Transplantation |
National Cancer Institute (NCI) |
2022-11-18 | PHASE1; PHASE2 |
| NCT05139004 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome; Secondary Acute Myeloid Leukemia |
City of Hope Medical Center |
2022-07-19 | PHASE1 |
| NCT03346135 | ACTIVE_NOT_RECRUITING | Plasma Cell Myeloma; Secondary Amyloidosis |
City of Hope Medical Center |
2019-07-17 | PHASE2 |
| NCT04370301 | RECRUITING | Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2021-02-09 | PHASE2 |
| NCT04872595 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia (AML); Acute Lymphoid Leukemia (ALL); Myelodysplastic Syndromes (MDS) |
Memorial Sloan Kettering Cancer Center |
2021-04-30 | PHASE2 |
| NCT03964506 | RECRUITING | Acute Myeloid Leukemia; Myelodysplastic Syndromes; Chronic Myelomonocytic Leukemia; Atypical Chronic Myeloid Leukemia; Chronic Monocytic Leukemia; Myelofibrosis; Myelodysplastic/Myeloproliferative Neoplasm |
Omar Aljitawi |
2020-07-01 | EARLY_PHASE1 |
| NCT03829371 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
University of Turin, Italy |
2019-01-03 | PHASE4 |
| NCT03579875 | RECRUITING | Fanconi Anemia; Severe Aplastic Anemia; Myelodysplastic Syndromes; T Cell Receptor Alpha/Beta Depletion; Telomere Biology Disorder; Bone Marrow Failure; Dyskeratosis Congenita; Telomere Biology Disorders |
Masonic Cancer Center, University of Minnesota |
2018-11-13 | PHASE2 |
| NCT01804634 | RECRUITING | Refractory and/or Relapsed Metastatic Solid Tumors |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2013-03-27 | PHASE2 |
| NCT06001385 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Acute Leukemia; Myelodysplastic Syndromes; Chronic Myeloid Leukemia; Chronic Lymphocytic Leukemia; Myeloproliferative Neoplasm; Lymphoma; Chronic Myelomonocytic Leukemia; Pro-Lymphocytic Leukemia; Myelofibrosis |
Center for International Blood and Marrow Transplant Research |
2023-12-08 | PHASE2 |
| NCT05436561 | RECRUITING | Disease-free Survival |
Shanghai Jiao Tong University School of Medicine |
2022-06-01 | PHASE2 |
| NCT06607458 | RECRUITING | Refractory Metastatic Colorectal Cancer |
Delcath Systems Inc. |
2025-08-05 | PHASE2 |
| NCT00692939 | RECRUITING | Crohn's Disease |
Paul Szabolcs |
2012-06-26 | PHASE1; PHASE2 |
| NCT06652165 | NOT_YET_RECRUITING | DLBCL |
Ruijin Hospital |
2024-11-01 | PHASE2 |
| NCT01962415 | RECRUITING | Primary Immunodeficiency (PID); Congenital Bone Marrow Failure Syndromes; Inherited Metabolic Disorders (IMD); Hereditary Anemias; Inflammatory Conditions; Systemic Juvenile Idiopathic Arthritis (sJIA); Juvenile Rheumatoid Arthritis (JRA) |
Paul Szabolcs |
2014-02-04 | PHASE2 |
| NCT03352765 | ACTIVE_NOT_RECRUITING | Lymphoma |
Memorial Sloan Kettering Cancer Center |
2017-11-20 | PHASE1 |
| NCT02605421 | RECRUITING | Neuroblastoma |
Masonic Cancer Center, University of Minnesota |
2016-06 | PHASE2 |
| NCT03494569 | SUSPENDED | Acute Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia; Acute Myeloid Leukemia in Remission; Hematopoietic Cell Transplantation Recipient; Minimal Residual Disease; Myelodysplastic Syndrome; Secondary Acute Myeloid Leukemia |
City of Hope Medical Center |
2018-07-06 | PHASE1 |
| NCT04098393 | ACTIVE_NOT_RECRUITING | Hematologic Malignancies |
Memorial Sloan Kettering Cancer Center |
2019-09-18 | PHASE1 |
| NCT06028828 | RECRUITING | Allogeneic Hematopoietic Stem Cell Transplantation; Allogeneic Stem Cell Transplantation; Hematologic Malignancies |
University of California, Irvine |
2023-09-11 | PHASE2 |
| NCT02909036 | ACTIVE_NOT_RECRUITING | Multiple Myeloma; Amyloidosis |
Memorial Sloan Kettering Cancer Center |
2016-09 | PHASE1 |
| NCT04904588 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Myelogenous Leukemia; Mixed Phenotype Acute Leukemia; Acute Leukemia; Myelodysplastic Syndromes; Chronic Myelogenous Leukemia; Chronic Lymphocytic Leukemia; Lymphoma |
Center for International Blood and Marrow Transplant Research |
2021-09-30 | PHASE2 |
| NCT06829472 | RECRUITING | Toxicities; Survivorship |
Shanghai Jiao Tong University School of Medicine |
2023-12-01 | PHASE3 |
| NCT02061800 | UNKNOWN | Chronic Myeloid Leukemia (CML); Acute Myelogenous Leukemia (AML); Myelodysplastic Syndrome (MDS); Juvenile Myelomonocytic Leukemia (JMML); Acute Lymphoblastic Leukemia (ALL); Lymphoma (Hodgkin's and Non-Hodgkin's) |
Diane George |
2013-06-03 | PHASE1; PHASE2 |
| NCT04384692 | ACTIVE_NOT_RECRUITING | Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2020-12-18 | PHASE2 |
| NCT05870995 | RECRUITING | Refractory Leukemia |
Shanghai Jiao Tong University School of Medicine |
2023-02-01 | PHASE2 |
| NCT05466318 | UNKNOWN | Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell |
Sichuan University |
2022-07-01 | PHASE3 |
| NCT00716066 | ACTIVE_NOT_RECRUITING | Autoimmune Disease; Neurologic Autoimmune Disease; Autologous Transplant Autoimmune; Multiple Sclerosis Transplant; MS Stem Cell Transplant; Multiple Sclerosis Stem Cell Transplant; Stiff Person Syndrome; HCT for Neurologic Autoimmune Disorders; CIDP Transplant; Myasthenia Gravis Transplant; Autoimmune Nervous System Disorder; Central Nervous System Vasculitis; Cerebellar Degeneration; Chronic Inflammatory Demyelinating Polyneuropathy; Lambert Eaton Myasthenic Syndrome; Myasthenia Gravis; Neuromyelitis Optica; Opsoclonus Myoclonus Syndrome; Rasmussen Subacute Encephalitis |
Fred Hutchinson Cancer Center |
2008-06 | PHASE2 |
| NCT05674539 | ENROLLING_BY_INVITATION | Acute Myeloid Leukemia, Adult; Myelodysplastic Syndrome(MDS); Allogeneic Hematopoietic Stem Cell Transplantation |
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
2023-02-15 | PHASE3 |
| NCT05893654 | ENROLLING_BY_INVITATION | Uveal Melanoma |
Hospital das Clínicas de Ribeirão Preto |
2021-05-01 | PHASE1; PHASE2 |
| NCT05991908 | RECRUITING | Acute Myeloid Leukemia; Myelodysplastic Syndromes |
Shanghai Jiao Tong University School of Medicine |
2023-10-19 | PHASE3 |
| NCT03188172 | UNKNOWN | Multiple Myeloma |
University of Leeds |
2017-09-28 | PHASE2 |
| NCT04812470 | COMPLETED | Metastatic Uveal Melanoma; Metastatic Cutaneous Melanoma |
Vastra Gotaland Region |
2023-02-06 | PHASE1 |
| NCT05518383 | RECRUITING | Non-hodgkin Lymphoma,B Cell; Burkitt Lymphoma; Primary Mediastinal Lymphoma; Primary CNS Lymphoma; Diffuse Large B-cell Lymphoma |
Federal Research Institute of Pediatric Hematology, Oncology and Immunology |
2022-05-25 | PHASE4 |
| NCT05115630 | COMPLETED | Myeloid Malignancies; Acute Myeloid Leukemia; Myelodysplastic Syndrome; Chronic Myeloid Leukemia |
M.D. Anderson Cancer Center |
2022-04-08 | PHASE2 |
| NCT06125483 | RECRUITING | Hematopoietic Malignancy; Relapse/Recurrence; Hematopoietic Stem Cell Transplantation |
The First Affiliated Hospital of Soochow University |
2023-11-01 | |
| NCT01821781 | ACTIVE_NOT_RECRUITING | Immune Deficiency Disorders; Severe Combined Immunodeficiency; Chronic Granulomatous Disease; X-linked Agammaglobulinemia; Wiskott-Aldrich Syndrome; Hyper-IgM; DiGeorge Syndrome; Chediak-Higashi Syndrome; Common Variable Immune Deficiency; Immune Dysregulatory Disorders; Hemophagocytic Lymphohistiocytosis; IPEX; Autoimmune Lymphoproliferative Syndrome; X-linked Lymphoproliferative Syndrome |
Washington University School of Medicine |
2013-04-29 | PHASE2 |
| NCT01758328 | COMPLETED | Multiple Myeloma |
Memorial Sloan Kettering Cancer Center |
2012-12 | PHASE1 |
| NCT06247917 | UNKNOWN | Myelodysplastic Syndrome With Excess Blasts-1; Myelodysplastic Syndrome With Excess Blasts-2; Myelodysplastic Syndromes |
Ruijin Hospital |
2024-03-03 | PHASE2 |
| NCT05903937 | NOT_YET_RECRUITING | Uveal Melanoma; Metastatic Cutaneous Melanoma |
Vastra Gotaland Region |
2023-12-31 | PHASE1 |
| NCT05855122 | UNKNOWN | Multiple Myeloma |
The First Affiliated Hospital of Soochow University |
2023-04-17 | PHASE4 |
| NCT04530487 | TERMINATED | Desmoplastic Small Round Cell Tumor; Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Recurrent Desmoplastic Small Round Cell Tumor; Recurrent Malignant Peripheral Nerve Sheath Tumor; Recurrent Malignant Solid Neoplasm; Recurrent Neuroblastoma; Recurrent Rhabdomyosarcoma; Refractory Desmoplastic Small Round Cell Tumor; Refractory Malignant Peripheral Nerve Sheath Tumor; Refractory Malignant Solid Neoplasm; Refractory Neuroblastoma; Refractory Rhabdomyosarcoma |
M.D. Anderson Cancer Center |
2020-08-19 | PHASE2 |
| NCT03849651 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia (ALL); Acute Myeloid Leukemia (AML); Myelodysplastic Syndromes (MDS); NK-Cell Leukemia; Hodgkin Lymphoma; Non Hodgkin Lymphoma (NHL); Juvenile Myelomonocytic Leukemia (JMML); Chronic Myeloid Leukemia (CML) |
St. Jude Children's Research Hospital |
2019-01-31 | PHASE2 |
| NCT03602235 | COMPLETED | Multiple Myeloma |
Christopher Strouse |
2019-03-05 | PHASE1 |
| NCT03073694 | UNKNOWN | Cancer, Appendiceal; ColoRectal Cancer |
University of Kansas Medical Center |
2017-07-14 | PHASE2 |
| NCT03346096 | COMPLETED | Malignant Lymphoma |
Sheba Medical Center |
2018-10-09 | PHASE2 |
| NCT01729091 | COMPLETED | Plasma Cell Leukemia; Plasma Cell Myeloma |
M.D. Anderson Cancer Center |
2013-06-10 | PHASE2 |
| NCT03342196 | COMPLETED | Leukemia |
Case Comprehensive Cancer Center |
2018-03-21 | PHASE2 |
| NCT02506959 | COMPLETED | Plasma Cell Leukemia; Plasmacytoma; Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
M.D. Anderson Cancer Center |
2015-09-14 | PHASE2 |
| NCT06313502 | Not yet recruiting | Plasma Cell Disorder |
University of Arkansas|University of Iowa |
2024-06 | Phase 1 |
| NCT00357565 | COMPLETED | Leukemia; Myelodysplastic Syndromes; Childhood Acute Myeloid Leukemia in Remission; Recurrent Childhood Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Childhood Acute Lymphoblastic Leukemia in Remission; Previously Treated Myelodysplastic Syndrome; Secondary Myelodysplastic Syndrome; Refractory Anemia With Excess Blasts in Transformation; Refractory Anemia With Excess Blasts; Refractory Anemia; De Novo Myelodysplastic Syndrome; Childhood Myelodysplastic Syndrome |
Masonic Cancer Center, University of Minnesota |
2005-11 | PHASE2 |
| NCT03615105 | TERMINATED | Acute Lymphoid Leukemia (ALL); Acute Myeloid Leukemia (AML); Chronic Myeloid Leukemia (CML); Hodgkin Lymphoma; Non-Hodgkin Lymphoma; Chronic Lymphocytic Leukemia |
Memorial Sloan Kettering Cancer Center |
2018-07-25 | PHASE2 |
| NCT05022901 | ACTIVE_NOT_RECRUITING | Metastatic Ocular Melanoma; Metastatic Uveal Melanoma |
Delcath Systems Inc. |
2022-06-10 | PHASE3 |
| NCT04191187 | COMPLETED | Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia; Biphenotypic Acute Leukemia; Undifferentiated Leukemia; Prolymphocytic Leukemia; Myelodysplastic Syndromes; Chronic Myelogenous Leukemia; Myeloproliferative Neoplasm; Relapsed Large Cell Lymphoma; Mantle Cell Lymphoma; Hodgkin Lymphoma; Burkitt Lymphoma; Relapsed T-Cell Lymphoma; Relapsed Chronic Lymphocytic Leukemia; Relapsed Small Lymphocytic Lymphoma; Relapsed Marginal B-cell Lymphoma; Relapsed Follicular Lymphoma; Lymphoplasmacytic Lymphoma |
H. Lee Moffitt Cancer Center and Research Institute |
2019-12-06 | PHASE2 |
| NCT01505569 | COMPLETED | Ewing's Family Tumors; Renal Tumors; Hepatoblastoma; Rhabdomyosarcoma; Soft Tissue Sarcoma; Primary Malignant Brain Neoplasms; Retinoblastoma; Medulloblastoma; Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET); Atypical Teratoid/Rhabdoid Tumor (AT/RT); CNS Tumors; Germ Cell Tumors |
Masonic Cancer Center, University of Minnesota |
2011-10-20 | |
| NCT00936936 | COMPLETED | Testicular Cancer |
M.D. Anderson Cancer Center |
2009-06-02 | PHASE2 |
| NCT04904237 | UNKNOWN | Refractory Acute Myeloid Leukemia |
Shanghai Jiao Tong University School of Medicine |
2021-01-01 | PHASE2 |
| NCT05438394 | UNKNOWN | Multiple Myeloma |
Peking University People's Hospital |
2022-10-13 | PHASE1 |
| NCT05013437 | WITHDRAWN | Multiple Myeloma |
Koen van Besien |
2023-09 | EARLY_PHASE1 |
| NCT02880293 | COMPLETED | Hematologic Malignancy |
Memorial Sloan Kettering Cancer Center |
2016-08-23 | |
| NCT03736616 | UNKNOWN | Diffuse Large B Cell Lymphoma |
Swedish Medical Center |
2019-08-16 | PHASE2 |
| NCT03192397 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia in Remission; Adult Acute Lymphoblastic Leukemia in Complete Remission; Chronic Myelogenous Leukemia, BCR-ABL1 Positive in Remission; Chronic Myelomonocytic Leukemia in Remission; Graft Versus Host Disease; Hodgkin Lymphoma; Minimal Residual Disease; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Non-Hodgkin Lymphoma; Plasma Cell Myeloma; Severe Aplastic Anemia; Waldenstrom Macroglobulinemia |
Roswell Park Cancer Institute |
2017-08-09 | PHASE1; PHASE2 |
| NCT01810588 | COMPLETED | Hematologic Malignancies |
Weill Medical College of Cornell University |
2012-10-16 | PHASE2 |
| NCT03742297 | ACTIVE_NOT_RECRUITING | Newly Diagnosed Multiple Myeloma |
PETHEMA Foundation |
2018-10-22 | PHASE3 |
| NCT04455139 | TERMINATED | Eye Cancer, Retinoblastoma |
Prof. Beck Popovic Maja |
2021-11-15 | PHASE2 |
| NCT02766465 | COMPLETED | Sickle Cell Disease |
Medical College of Wisconsin |
2017-03-16 | PHASE2 |
| NCT02960646 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Aplastic Anemia; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Lymphoblastic Lymphoma; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Plasma Cell Myeloma; Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma; Recurrent Hodgkin Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma; Therapy-Related Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2017-01-18 | PHASE1 |
| NCT02295722 | TERMINATED | Hodgkin's Lymphoma - Relapsed/Refractory; Non-Hodgkin's Lymphoma - Aggressive; Follicular Lymphoma |
AHS Cancer Control Alberta |
2015-04 | PHASE1; PHASE2 |
| NCT04342572 | COMPLETED | Retinoblastoma |
Washington University School of Medicine |
2020-08-11 | PHASE1 |
| NCT03086993 | UNKNOWN | Bile Duct Cancer; Intrahepatic Cholangiocarcinoma |
Delcath Systems Inc. |
2018-04-10 | PHASE2; PHASE3 |
| NCT02866136 | ACTIVE_NOT_RECRUITING | Retinoblastoma; Children; Retinal Neoplasm |
Institut Curie |
2012-02 | PHASE2 |
| NCT02700841 | TERMINATED | Plasma Cell Myeloma |
University of Nebraska |
2020-01-09 | PHASE2 |
| NCT04682405 | COMPLETED | Multiple Myeloma |
Washington University School of Medicine |
2021-05-05 | PHASE2 |
| NCT03795597 | UNKNOWN | Multiple Myeloma |
Loyola University |
2019-05-22 | PHASE1; PHASE2 |
| NCT05084027 | UNKNOWN | Hematologic Malignancy; Older Patients; Allogeneic Hematopoietic Stem Cell Transplantation |
First Affiliated Hospital of Zhejiang University |
2021-10-07 | PHASE2 |
| NCT04395222 | ACTIVE_NOT_RECRUITING | Hematologic Malignancy; Bone Marrow Transplant |
Weill Medical College of Cornell University |
2020-10-07 | PHASE2 |
| NCT02771197 | COMPLETED | Acute Myeloid Leukemia |
Northside Hospital, Inc. |
2016-09-28 | PHASE2 |
| NCT02994784 | TERMINATED | Amyloidosis; Systemic |
Boston Medical Center |
2018-01-08 | PHASE2 |
| NCT00551928 | COMPLETED | Multiple Myeloma; Newly Diagnosed Patients |
Fondazione EMN Italy Onlus |
2007-06 | PHASE3 |
| NCT01904136 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia With Gene Mutations; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; de Novo Myelodysplastic Syndrome; Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Therapy-Related Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2014-04-22 | PHASE1; PHASE2 |
| NCT04115956 | TERMINATED | AL Amyloidosis |
Oncopeptides AB |
2020-08-06 | PHASE1 |
| NCT02867800 | COMPLETED | Sickle Cell Disease; Graft Versus Host Disease |
Monica Bhatia |
2016-07 | PHASE1 |
| NCT02939287 | COMPLETED | Nausea; Vomiting |
Rush University Medical Center |
2017-09-23 | PHASE3 |
| NCT03639610 | TERMINATED | Renal Impairment; Multiple Myeloma |
Oncopeptides AB |
2018-08-28 | PHASE2 |
| NCT04278040 | UNKNOWN | Non-cystic Fibrosis Bronchiectasis |
Federal State Budgetary Institution, Pulmonology Scientific Research Institute |
2018-06-20 | PHASE2 |
| NCT01554852 | UNKNOWN | Multiple Myeloma |
University of Leeds |
2010-05 | PHASE3 |
| NCT04455139 | Terminated | Eye Cancer Retinoblastoma |
Prof. Beck Popovic Maja|University of Lausanne Hospitals |
2021-11-15 | Phase 2 |
| NCT01054196 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
Weill Medical College of Cornell University |
2010-08 | PHASE1; PHASE2 |
| NCT03583424 | COMPLETED | Hematopoietic Cell Transplantation Recipient; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Non-Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma; Refractory Marginal Zone Lymphoma; Refractory Non-Hodgkin Lymphoma; Refractory Transformed Indolent Non-Hodgkin Lymphoma |
Ohio State University Comprehensive Cancer Center |
2018-09-10 | PHASE1; PHASE2 |
| NCT01091831 | COMPLETED | Multiple Myeloma |
Fondazione EMN Italy Onlus |
2009-07 | PHASE3 |
| NCT02544425 | UNKNOWN | Extranodal NK-T-Cell Lymphoma |
Samsung Medical Center |
2016-02-21 | PHASE2 |
| NCT01807611 | COMPLETED | Leukemia; Lymphoma |
St. Jude Children's Research Hospital |
2013-05-16 | PHASE2 |
| NCT03555032 | COMPLETED | Melanoma and Sarcoma |
Royal Marsden NHS Foundation Trust |
2018-06-26 | PHASE1; PHASE2 |
| NCT00423514 | COMPLETED | Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes |
Memorial Sloan Kettering Cancer Center |
2006-11-20 | PHASE1; PHASE2 |
| NCT04412707 | TERMINATED | RRMM |
Oncopeptides AB |
2020-08-04 | PHASE2 |
| NCT04945954 | Not yet recruiting | Hematopoietic Stem Cell Transplantation |
Seoul National University Hospital|National Institute of Food and Drug Safety Evaluation (Republic of Korea) |
2021-06 | Not Applicable |
| NCT02961816 | WITHDRAWN | Lymphoma |
M.D. Anderson Cancer Center |
2017-06 | PHASE2 |
| NCT04205240 | TERMINATED | Recurrent Plasma Cell Myeloma |
Srinivas Devarakonda |
2020-12-22 | PHASE2 |
| NCT00303849 | COMPLETED | Anaplastic Oligoastrocytoma; Anaplastic Oligodendroglioma; Mixed Glioma; Oligoastrocytoma |
OHSU Knight Cancer Institute |
2005-09-15 | PHASE1; PHASE2 |
| NCT02784054 | UNKNOWN | Intracranial Non-germinomatous Germ Cell Tumor |
Samsung Medical Center |
2014-04 | PHASE2 |
| NCT02780609 | COMPLETED | Multiple Myeloma |
H. Lee Moffitt Cancer Center and Research Institute |
2017-07-20 | PHASE1; PHASE2 |
| NCT01208766 | COMPLETED | Multiple Myeloma |
Stichting Hemato-Oncologie voor Volwassenen Nederland |
2011-01 | PHASE3 |
| NCT03385096 | UNKNOWN | Autologous Hematopoietic Stem Cell Transplantation; Conditioning; Multiple Myeloma |
Nanfang Hospital, Southern Medical University |
2018-01-02 | PHASE2; PHASE3 |
| NCT03615144 | TERMINATED | Non-Malignant Hematologic Disorders |
Memorial Sloan Kettering Cancer Center |
2018-07-23 | PHASE2 |
| NCT02963493 | COMPLETED | Multiple Myeloma |
Oncopeptides AB |
2016-12-28 | PHASE2 |
| NCT00629798 | COMPLETED | Acute Myeloid Leukemia; Advanced Myelodysplastic Syndromes |
Memorial Sloan Kettering Cancer Center |
2008-02-12 | PHASE2 |
| NCT01794572 | TERMINATED | Multiple Myeloma in Relapse |
Institut Cancerologie de l'Ouest |
2013-04-09 | |
| NCT02440464 | COMPLETED | Multiple Myeloma |
National Heart, Lung, and Blood Institute (NHLBI) |
2015-08 | PHASE2 |
| NCT01849783 | COMPLETED | Extramedullary Plasmacytoma; Isolated Plasmacytoma of Bone; Light Chain Deposition Disease; Primary Systemic Amyloidosis; Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma |
Margarida Magalhaes-Silverman |
2013-04-04 | PHASE2 |
| NCT02342782 | COMPLETED | Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma; Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma; Refractory Cutaneous T-Cell Non-Hodgkin Lymphoma |
City of Hope Medical Center |
2020-06-08 | PHASE1 |
| NCT03412565 | COMPLETED | Multiple Myeloma |
Janssen Research & Development, LLC |
2018-04-26 | PHASE2 |
| NCT00177047 | COMPLETED | Multiple Myeloma |
Masonic Cancer Center, University of Minnesota |
2004-04-20 | PHASE2; PHASE3 |
| NCT03128359 | COMPLETED | Acute Leukemia; Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Diffuse Large B-Cell Lymphoma; Follicular Lymphoma; Graft Versus Host Disease; Hodgkin Lymphoma; Mantle Cell Lymphoma; Marginal Zone Lymphoma; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes; Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma; Secondary Myelodysplastic Syndrome |
City of Hope Medical Center |
2017-05-30 | PHASE2 |
| NCT03003728 | WITHDRAWN | Multiple Myeloma |
University of Arkansas |
2019-11-01 | PHASE2 |
| NCT03217812 | COMPLETED | Multiple Myeloma |
Janssen Research & Development, LLC |
2017-11-23 | PHASE3 |
| NCT03674411 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia; Acute Lymphocytic Leukemia; Biphenotypic/Undifferentiated Leukemia; Chronic Myelogenous Leukemia; Myelodysplasia; Relapsed Large Cell Lymphoma; Mantle Cell Lymphoma; Hodgkin Lymphoma; Burkitt Lymphoma; Relapsed T-Cell Lymphoma; Lymphoplasmacytic Lymphoma |
Masonic Cancer Center, University of Minnesota |
2019-01-02 | PHASE2 |
| NCT02497404 | COMPLETED | Leukemia, Erythroblastic, Acute; Myelodysplastic Syndromes |
Weill Medical College of Cornell University |
2015-02-13 | PHASE2 |
| NCT01453101 | COMPLETED | Multiple Myeloma |
Hackensack Meridian Health |
2010-06-09 | PHASE2 |
| NCT00968760 | COMPLETED | Lymphoma; B-cell Lymphoma |
M.D. Anderson Cancer Center |
2011-06-20 | PHASE1 |
| NCT02917096 | COMPLETED | Primary Myelofibrosis; Secondary Myelofibrosis |
City of Hope Medical Center |
2016-11-13 | PHASE1 |
| NCT03233776 | COMPLETED | Multiple Myeloma |
Radboud University Medical Center |
2017-08-21 | PHASE2 |
| NCT02416206 | COMPLETED | Multiple Myeloma |
Northside Hospital, Inc. |
2015-04-27 | PHASE2 |
| NCT03187223 | COMPLETED | Multiple Myeloma |
Insel Gruppe AG, University Hospital Bern |
2017-07-20 | PHASE2 |
| NCT00591630 | COMPLETED | Diffuse Large Cell Lymphoma; Lymphoma |
M.D. Anderson Cancer Center |
2007-11-14 | PHASE2 |
| NCT02756572 | COMPLETED | Blasts 10 Percent or More of Bone Marrow Nucleated Cells; Chronic Myelomonocytic Leukemia-2; High Grade Malignant Neoplasm; Myelodysplastic Syndrome; Myelodysplastic Syndrome With Excess Blasts-2; Myeloid Neoplasm; Previously Treated Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
University of Washington |
2016-09-22 | PHASE2 |
| NCT01625351 | COMPLETED | Ewing Sarcoma; Gastrointestinal Tumor; Germ Cell Tumor; Hepatic Tumor; Lymphoma; Wilms Tumor; Rhabdoid Tumor; Clear Cell Carcinoma; Renal Cell Carcinoma; Melanoma; Neuroblastoma; Rhabdomyosarcoma; Non-rhabdomyosarcoma |
St. Jude Children's Research Hospital |
2012-08-20 | PHASE1 |
| NCT01090089 | COMPLETED | Multiple Myeloma |
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH |
2010-03-01 | PHASE3 |
| NCT04008888 | UNKNOWN | Multiple Myeloma; Plasma Cell Leukemia; Extramedullary Plasmacytoma; Loss of Chromosome 17p; t(14;16); t(4;14); T(14;20); 1Q21 Amplification; Complex Karyotype |
Institute of Hematology & Blood Diseases Hospital, China |
2018-01-05 | |
| NCT01885689 | ACTIVE_NOT_RECRUITING | Adult Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Adult Acute Myeloid Leukemia in Remission; Myelodysplastic Syndrome; Secondary Myelodysplastic Syndrome; Chronic Myelomonocytic Leukemia; Therapy-Related Myelodysplastic Syndrome |
City of Hope Medical Center |
2014-02-10 | PHASE2 |
| NCT02059239 | COMPLETED | Hodgkin's Lymphoma; Non-Hodgkin's Lymphoma |
Weill Medical College of Cornell University |
2014-06-04 | PHASE1; PHASE2 |
| NCT03579927 | WITHDRAWN | CD19 Positive; Mantle Cell Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma |
M.D. Anderson Cancer Center |
2019-10-03 | PHASE1; PHASE2 |
| NCT01163357 | COMPLETED | Autologous Hematopoietic Stem Cell Transplant Recipient; Loss of Chromosome 17p; Plasma Cell Leukemia; Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
City of Hope Medical Center |
2011-01-28 | PHASE1 |
| NCT03506802 | WITHDRAWN | HLA-A*0201 Positive Cells Present; NY-ESO-1 Positive Tumor Cells Present; Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Jonsson Comprehensive Cancer Center |
2018-07-10 | PHASE1 |
| NCT00577278 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma |
City of Hope Medical Center |
2007-10-03 | PHASE2 |
| NCT02116959 | TERMINATED | Advanced Intra-Ocular Retinoblastoma; Retinoblastoma |
University of California, San Francisco |
2014-07-23 | PHASE1 |
| NCT02919670 | COMPLETED | Multiple Myeloma; Non-Hodgkin's Lymphoma |
Dana-Farber Cancer Institute |
2016-10 | |
| NCT01413178 | COMPLETED | Myeloma |
M.D. Anderson Cancer Center |
2011-09-30 | PHASE3 |
| NCT02435901 | COMPLETED | Sickle Cell Disease; Beta Thalassemia-Major |
Northwell Health |
2008-12 | PHASE1; PHASE2 |
| NCT02896582 | COMPLETED | Mantle Cell Lymphoma |
The Lymphoma Academic Research Organisation |
2016-11-29 | PHASE2 |
| NCT00112827 | COMPLETED | Refractory Multiple Myeloma; Smoldering Multiple Myeloma; Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma |
City of Hope Medical Center |
2004-11 | PHASE1; PHASE2 |
| NCT02197221 | COMPLETED | Multiple Myeloma |
University Hospital, Toulouse |
2015-01 | PHASE3 |
| NCT03259516 | TERMINATED | Myelodysplastic Syndromes |
St. Petersburg State Pavlov Medical University |
2017-05-25 | PHASE1; PHASE2 |
| NCT01200329 | COMPLETED | Lymphoma |
M.D. Anderson Cancer Center |
2011-06 | PHASE2 |
| NCT03704597 | UNKNOWN | Myeloma; Mucositis; Cryotherapy Effect |
Sahlgrenska University Hospital |
2014-03-01 | |
| NCT02114502 | WITHDRAWN | Myeloma |
M.D. Anderson Cancer Center |
2014-09 | PHASE2 |
| NCT00943800 | COMPLETED | Leukemia; Myelodysplastic Syndrome; Multiple Myeloma; Lymphoma |
University of Chicago |
2006-10-09 | |
| NCT00536601 | COMPLETED | Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor (PNET); Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Peripheral T-cell Lymphoma; Plasma Cell Neoplasm; Primary Systemic Amyloidosis; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Malignant Testicular Germ Cell Tumor; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Neuroblastoma; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Multiple Myeloma; Regional Neuroblastoma; Splenic Marginal Zone Lymphoma; Testicular Lymphoma; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific; Waldenström Macroglobulinemia |
Roswell Park Cancer Institute |
2006-06-29 | |
| NCT02415413 | ACTIVE_NOT_RECRUITING | Smoldering Multiple Myeloma |
PETHEMA Foundation |
2015-05 | PHASE2 |
| NCT01008462 | COMPLETED | B-Cell Prolymphocytic Leukemia; Hypodiploidy; Loss of Chromosome 17p; Plasma Cell Leukemia; Progression of Multiple Myeloma or Plasma Cell Leukemia; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Non-Hodgkin Lymphoma; Recurrent Childhood Hodgkin Lymphoma; Recurrent Childhood Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Plasma Cell Myeloma; Recurrent Small Lymphocytic Lymphoma; Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Non-Hodgkin Lymphoma; Refractory Plasma Cell Myeloma; Refractory Small Lymphocytic Lymphoma; t(14;16); t(4;14); T-Cell Prolymphocytic Leukemia; Waldenstrom Macroglobulinemia |
Fred Hutchinson Cancer Center |
2010-03-18 | PHASE2 |
| NCT02572492 | UNKNOWN | Multiple Myeloma |
Henrik Gregersen |
2015-01 | PHASE2 |
| NCT01637766 | COMPLETED | Spinal Diseases; Spinal Metastases; Spinal Tumors |
Weill Medical College of Cornell University |
2012-04 | PHASE1 |
| NCT01605032 | COMPLETED | DS Stage I Plasma Cell Myeloma; DS Stage II Plasma Cell Myeloma; DS Stage III Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Albert Einstein College of Medicine |
2012-02 | PHASE2 |
| NCT02206425 | COMPLETED | Multiple Myeloma |
Oncotherapeutics |
2014-09 | PHASE1; PHASE2 |
| NCT00004088 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
City of Hope Medical Center |
1999-04-13 | PHASE2 |
| NCT01824693 | COMPLETED | Juvenile Myelomonocytic Leukemia |
Children's Oncology Group |
2013-06-24 | PHASE2 |
| NCT02130869 | COMPLETED | Neuroblastoma; Lymphoma; High-risk Tumor |
St. Jude Children's Research Hospital |
2014-10-10 | PHASE1 |
| NCT00906113 | UNKNOWN | Retinoblastoma |
Hadassah Medical Organization |
2011-06 | PHASE1; PHASE2 |
| NCT02406508 | WITHDRAWN | Hepatocellular Carcinoma (HCC) |
Delcath Systems Inc. |
2014-10 | PHASE2 |
| NCT01983969 | COMPLETED | Advanced Cancers; Lymphoma |
M.D. Anderson Cancer Center |
2013-11-07 | PHASE1; PHASE2 |
| NCT02195479 | COMPLETED | Multiple Myeloma |
Janssen Research & Development, LLC |
2014-12-09 | PHASE3 |
| NCT01598025 | TERMINATED | Acute Leukemia; Chronic Leukemia; Myelodysplastic Syndrome; Non-Hodgkins Lymphoma |
Memorial Sloan Kettering Cancer Center |
2012-05-02 | |
| NCT01010217 | COMPLETED | Blood Stem Cell Transplant Failure; Leukemia; Hematologic Malignancies |
M.D. Anderson Cancer Center |
2009-11-05 | PHASE2 |
| NCT01237951 | COMPLETED | Myeloma |
M.D. Anderson Cancer Center |
2010-11-08 | PHASE2 |
| NCT02653196 | TERMINATED | Neuroepithelial Tumor; Solid Tumor; Allogeneic Hematopoietic Stem Cell Transplantation |
Montefiore Medical Center |
2015-09 | EARLY_PHASE1 |
| NCT01035463 | COMPLETED | Anaplastic Large Cell Lymphoma, ALK-Negative; Recurrent Anaplastic Large Cell Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Transformed Non-Hodgkin Lymphoma |
University of Nebraska |
2009-11-12 | PHASE1; PHASE2 |
| NCT01408563 | COMPLETED | Non-Hodgkin's Lymphoma; Hodgkin's Lymphoma; Multiple Myeloma; Chronic Lymphocytic Leukemia; Acute Myelogenous Leukemia |
Massachusetts General Hospital |
2011-12 | PHASE2 |
| NCT02331368 | COMPLETED | Multiple Myeloma |
University of Michigan Rogel Cancer Center |
2015-06 | PHASE2 |
| NCT03794167 | COMPLETED | Non-hodgkin Lymphoma |
Soonchunhyang University Hospital |
2012-06-01 | PHASE2 |
| NCT02750254 | TERMINATED | Acute Myeloid Leukemia; Myelodysplastic Syndrome; Acute Lymphocytic Leukemia |
Washington University School of Medicine |
2016-06-27 | PHASE1 |
| NCT02199041 | TERMINATED | Hematological Malignancies |
St. Jude Children's Research Hospital |
2014-07-11 | PHASE2 |
| NCT01688401 | COMPLETED | Diffuse Intrinsic Pontine Glioma (DIPG) |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2013-03-08 | PHASE1 |
| NCT02489500 | TERMINATED | AL Amyloidosis |
Boston Medical Center |
2015-06 | PHASE3 |
| NCT01471067 | COMPLETED | Blood And Marrow Transplantation; Leukemia; Lymphoma; Transplantation Infection; Transplantation, Bone Marrow |
M.D. Anderson Cancer Center |
2012-07-13 | PHASE1 |
| NCT01731886 | COMPLETED | Multiple Myeloma |
Columbia University |
2012-09 | PHASE4 |
| NCT01875237 | TERMINATED | Leukemia; Myeloma; Myeloproliferative Diseases |
M.D. Anderson Cancer Center |
2013-12-27 | PHASE1; PHASE2 |
| NCT02614560 | TERMINATED | Acute Myeloid Leukemia |
Seagen Inc. |
2015-11 | PHASE1; PHASE2 |
| NCT01907009 | TERMINATED | Castrate Resistant Prostate Cancer |
Barts & The London NHS Trust |
2013-01 | PHASE2; PHASE3 |
| NCT00526318 | UNKNOWN | Neuroblastoma |
German Society for Pediatric Oncology and Hematology GPOH gGmbH |
2007-01 | |
| NCT02043860 | TERMINATED | Multiple Myeloma |
University of Illinois at Chicago |
2014-01-10 | PHASE1 |
| NCT01410344 | COMPLETED | Leukemia; Lymphoma; HIV |
Medical College of Wisconsin |
2011-09 | PHASE2 |
| NCT00498316 | COMPLETED | Myelodysplastic Syndrome; Leukemia |
M.D. Anderson Cancer Center |
2007-07-03 | PHASE1 |
| NCT02366663 | TERMINATED | Recurrent Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma |
City of Hope Medical Center |
2015-01 | PHASE3 |
| NCT01969942 | WITHDRAWN | Ewing Sarcoma |
University of Louisville |
2013-04 | PHASE1 |
| NCT00793572 | COMPLETED | Refractory Plasma Cell Myeloma |
Fred Hutchinson Cancer Center |
2008-10 | PHASE2 |
| NCT01175356 | COMPLETED | Ganglioneuroblastoma; Localized Resectable Neuroblastoma; Localized Unresectable Neuroblastoma; Regional Neuroblastoma; Stage 4 Neuroblastoma; Stage 4S Neuroblastoma |
Children's Oncology Group |
2011-12-21 | PHASE1 |
| NCT02043847 | COMPLETED | Multiple Myeloma, Relapsed; Multiple Myeloma, Refractory to Standard Treatment |
University of Illinois at Chicago |
2014-01-14 | PHASE1 |
| NCT02528877 | WITHDRAWN | Acute Myeloid Leukemia in Remission; Primary Myelofibrosis; Primary Myelofibrosis, Prefibrotic Stage; Secondary Acute Myeloid Leukemia; Secondary Myelofibrosis |
City of Hope Medical Center |
2015-11 | PHASE1 |
| NCT01040026 | COMPLETED | Multiple Myeloma |
University Hospital, Basel, Switzerland |
2012-10 | PHASE1; PHASE2 |
| NCT01293539 | TERMINATED | Retinoblastoma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2011-03 | PHASE2 |
| NCT00689936 | COMPLETED | Multiple Myeloma |
Celgene |
2008-08-21 | PHASE3 |
| NCT00067002 | COMPLETED | Leukemia, Lymphocytic, Acute; Leukemia, Myelocytic, Acute; Leukemia, Myeloid, Chronic; Lymphoma, Non-Hodgkin |
M.D. Anderson Cancer Center |
2003-04 | PHASE2 |
| NCT00006244 | COMPLETED | Refractory Multiple Myeloma; Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma |
Fred Hutchinson Cancer Center |
2000-02 | PHASE2 |
| NCT00916058 | COMPLETED | Multiple Myeloma |
Weill Medical College of Cornell University |
2009-04-23 | PHASE1; PHASE2 |
| NCT00920153 | TERMINATED | Lymphoma |
French Innovative Leukemia Organisation |
2008-05 | PHASE3 |
| NCT01936090 | COMPLETED | DS Stage I Plasma Cell Myeloma; DS Stage II Plasma Cell Myeloma; DS Stage III Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Mayo Clinic |
2013-08 | PHASE1 |
| NCT01277016 | COMPLETED | AL Amyloidosis |
European Myeloma Network B.V. |
2011-01 | PHASE3 |
| NCT01531244 | WITHDRAWN | Melanoma |
Washington University School of Medicine |
2014-12 | PHASE1; PHASE2 |
| NCT00005803 | COMPLETED | Prolymphocytic Leukemia; Recurrent Adult Hodgkin Lymphoma; Recurrent Childhood Hodgkin Lymphoma; Recurrent Childhood Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Non-Hodgkin Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hodgkin Lymphoma; Refractory Non-Hodgkin Lymphoma; Refractory Small Lymphocytic Lymphoma; T-Cell Chronic Lymphocytic Leukemia; T-Cell Prolymphocytic Leukemia |
Fred Hutchinson Cancer Center |
1999-09 | PHASE1; PHASE2 |
| NCT00651937 | COMPLETED | Multiple Myeloma; Primary Amyloidosis |
M.D. Anderson Cancer Center |
2008-03 | PHASE2 |
| NCT00961142 | TERMINATED | Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia |
University Hospital Tuebingen |
2009-06 | PHASE2 |
| NCT02115243 | COMPLETED | Unresectable Melanoma |
Duke University |
2014-05 | PHASE1 |
| NCT01665014 | UNKNOWN | Multiple Myeloma |
Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice |
2012-08 | PHASE2 |
| NCT00253721 | TERMINATED | Brain and Central Nervous System Tumors; Lymphoma; Metastatic Cancer |
OHSU Knight Cancer Institute |
1998-05 | PHASE1 |
| NCT01272817 | COMPLETED | Aplastic Anemia; Paroxysmal Nocturnal Hemoglobinuria; Acute Myelogenous Leukemia; Acute Lymphocytic Leukemia; Myelodysplastic Syndrome; Chronic Myelogenous Leukemia; Chronic Lymphocytic Leukemia; Hodgkin's Lymphoma; Non-Hodgkin's Lymphoma; Mantle Cell Lymphoma; Multiple Myeloma; Waldenstrom Macroglobulinemia; Breast Cancer; Renal Cell Carcinoma; Melanoma; Sarcoma; Ovarian Cancer; Thymoma |
Scripps Health |
2001-10 | |
| NCT00238433 | COMPLETED | Lymphoma |
OHSU Knight Cancer Institute |
2005-03 | PHASE2 |
| NCT01141712 | COMPLETED | Lymphoma; HIV |
Medical College of Wisconsin |
2010-04 | PHASE2 |
| NCT01617213 | TERMINATED | Multiple Myeloma |
University of Virginia |
2012-04 | PHASE2 |
| NCT02259348 | TERMINATED | Acute Lymphoblastic Leukemia (ALL); Acute Myeloid Leukemia (AML); Myeloid Sarcoma; Chronic Myelogenous Leukemia (CML); Juvenile Myelomonocytic Leukemia (JMML); Myelodysplastic Syndrome (MDS); Non-Hodgkin Lymphoma (NHL) |
St. Jude Children's Research Hospital |
2014-10 | PHASE2 |
| NCT00567567 | COMPLETED | Localized Resectable Neuroblastoma; Localized Unresectable Neuroblastoma; Recurrent Neuroblastoma; Regional Neuroblastoma; Stage 4 Neuroblastoma; Stage 4S Neuroblastoma |
Children's Oncology Group |
2007-11-05 | PHASE3 |
| NCT02072863 | COMPLETED | Multiple Myeloma |
Amgen |
2014-01 | PHASE1; PHASE2 |
| NCT01255527 | UNKNOWN | Multiple Myeloma Patients Who Candidate for Autologous Peripheral Blood Stem Cell Transplantation |
Yonsei University |
2010-10 | PHASE1; PHASE2 |
| NCT01178658 | UNKNOWN | Non-Hodgkin Lymphoma |
Seoul National University Hospital |
2010-07 | PHASE2 |
| NCT00005835 | COMPLETED | Neuroblastoma |
New Approaches to Neuroblastoma Therapy Consortium |
2001-08 | PHASE1 |
| NCT00209222 | UNKNOWN | Lymphoma, Mantle-Cell |
European Mantle Cell Lymphoma Network |
2004-07 | PHASE3 |
| NCT01045460 | COMPLETED | Multiple Myeloma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2010-01-15 | PHASE2 |
| NCT00233987 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
2005-10 | PHASE2 |
| NCT00182793 | COMPLETED | Breast Cancer |
City of Hope Medical Center |
2005-07 | PHASE2 |
| NCT00550784 | COMPLETED | Fallopian Tube Cancer; Ovarian Cancer; Peritoneal Cavity Cancer |
City of Hope Medical Center |
2001-01 | PHASE1 |
| NCT01746173 | TERMINATED | T-cell Non-Hodgkin Lymphoma |
Dana-Farber Cancer Institute |
2013-07 | PHASE2 |
| NCT00383448 | COMPLETED | Adrenoleukodystrophy; Metachromatic Leukodystrophy; Globoid Cell Leukodystrophy; Tay Sachs Disease; Sandhoffs Disease; Wolman Disease; I-Cell Disease; Sanfilippo Syndrome; GM1 Gangliosidosis |
Masonic Cancer Center, University of Minnesota |
2006-09 | PHASE2 |
| NCT01182233 | TERMINATED | Multiple Myeloma |
University of Rochester |
2010-06 | PHASE1 |
| NCT00081939 | COMPLETED | Multiple Myeloma |
University of Arkansas |
2004-01 | PHASE2 |
| NCT00002601 | COMPLETED | Sarcoma |
City of Hope Medical Center |
1994-09 | PHASE2 |
| NCT01752257 | COMPLETED | Melanoma |
Douglas Tyler |
2012-07 | PHASE1 |
| NCT01063439 | UNKNOWN | Non Hodgkin's Lymphoma |
Inje University |
2010-01 | PHASE2 |
| NCT01237249 | COMPLETED | Multiple Myeloma |
PETHEMA Foundation |
2011-02 | PHASE2 |
| NCT01518153 | TERMINATED | Leukemia; Lymphoma; Myeloma; Myeloproliferative Diseases |
M.D. Anderson Cancer Center |
2012-02 | PHASE2 |
| NCT00564200 | COMPLETED | Multiple Myeloma |
PETHEMA Foundation |
2007-11 | PHASE2 |
| NCT01063179 | COMPLETED | Multiple Myeloma |
Fondazione EMN Italy Onlus |
2006-05 | PHASE3 |
| NCT01572688 | UNKNOWN | Multiple Myeloma |
Shandong Lanjin Pharmaceuticals Co.,Ltd |
2011-11 | |
| NCT00566098 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2007-11 | PHASE1; PHASE2 |
| NCT00691015 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Barbara Ann Karmanos Cancer Institute |
2008-05 | PHASE2 |
| NCT00997386 | COMPLETED | Hematologic Neoplasms; Multiple Myeloma; Anemia, Aplastic; Hemoglobinuria, Paroxysmal; Myelofibrosis |
University of Arizona |
2009-09 | PHASE2 |
| NCT00857519 | COMPLETED | Retinoblastoma |
Wills Eye |
2009-01 | |
| NCT00317408 | UNKNOWN | Lymphoma |
European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma |
2004-04 | |
| NCT01658904 | TERMINATED | Multiple Myeloma; Leukemia, Plasma Cell |
National Cancer Institute (NCI) |
2012-07 | PHASE1; PHASE2 |
| NCT01660633 | COMPLETED | Multiple Myeloma |
Acrotech Biopharma Inc. |
2012-12 | PHASE2 |
| NCT01279694 | COMPLETED | Myeloma |
Nantes University Hospital |
2010-10 | PHASE1; PHASE2 |
| NCT00602641 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
National Cancer Institute (NCI) |
2008-02-29 | PHASE3 |
| NCT01923935 | UNKNOWN | Multiple Myeloma |
Chonnam National University Hospital |
2013-01 | PHASE2 |
| NCT03061656 | UNKNOWN | High Risk Neuroblastoma |
Samsung Medical Center |
2009-01-01 | PHASE2 |
| NCT00784823 | COMPLETED | Multiple Myeloma |
Hackensack Meridian Health |
2007-01 | PHASE1; PHASE2 |
| NCT01500161 | TERMINATED | Acute Myelogenous Leukemia; Acute Lymphocytic Leukemia; Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia; Hodgkins Disease; Non-Hodgkins Lymphoma; Aplastic Anemia; Multiple Myeloma; Myelodysplastic Syndrome |
Texas Oncology Cancer Center |
2011-11 | PHASE2 |
| NCT00637767 | TERMINATED | Multiple Myeloma and Plasma Cell Neoplasm |
University of Southampton |
2007-12-01 | PHASE2 |
| NCT00544466 | ACTIVE_NOT_RECRUITING | Leukemia; Myelodysplastic Syndromes |
City of Hope Medical Center |
2006-07-31 | PHASE1; PHASE2 |
| NCT01653418 | TERMINATED | Multiple Myeloma |
Washington University School of Medicine |
2012-09 | PHASE2 |
| NCT00325416 | COMPLETED | Multiple Myeloma |
H. Lee Moffitt Cancer Center and Research Institute |
2001-11-19 | PHASE1; PHASE2 |
| NCT00890500 | COMPLETED | Hematologic Malignancies; Allogeneic Stem Cell Transplantation |
Fate Therapeutics |
2011-01 | PHASE1 |
| NCT00505895 | COMPLETED | Multiple Myeloma |
M.D. Anderson Cancer Center |
2002-01 | PHASE2 |
| NCT00507416 | COMPLETED | Multiple Myeloma |
Millennium Pharmaceuticals, Inc. |
2007-06 | PHASE3 |
| NCT00114101 | ACTIVE_NOT_RECRUITING | DS Stage I Multiple Myeloma; DS Stage II Multiple Myeloma; DS Stage III Multiple Myeloma; Refractory Multiple Myeloma; Smoldering Multiple Myeloma |
National Cancer Institute (NCI) |
2004-12-15 | PHASE3 |
| NCT01393769 | TERMINATED | Retinoblastoma |
Hospital Sant Joan de Deu |
2009-11 | PHASE2 |
| NCT00084695 | UNKNOWN | Childhood Langerhans Cell Histiocytosis; Fanconi Anemia; Leukemia; Lymphoma; Myelodysplastic Syndromes; Neuroblastoma; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific |
Milton S. Hershey Medical Center |
2003-09 | PHASE2 |
| NCT00691704 | COMPLETED | Multiple Myeloma |
Cristina Gasparetto |
2008-08 | PHASE2 |
| NCT00253435 | COMPLETED | Neuroblastoma |
New Approaches to Neuroblastoma Therapy Consortium |
2005-09 | PHASE2 |
| NCT01078454 | COMPLETED | Light Chain Deposition Disease; Primary Systemic Amyloidosis |
National Cancer Institute (NCI) |
2010-11 | PHASE3 |
| NCT00824135 | COMPLETED | Hematologic Malignancies |
St. Jude Children's Research Hospital |
2009-01 | PHASE1 |
| NCT00217438 | COMPLETED | Refractory Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma |
Fred Hutchinson Cancer Center |
2005-07 | PHASE3 |
| NCT00539500 | TERMINATED | Neuroblastoma |
M.D. Anderson Cancer Center |
2007-10 | PHASE2; PHASE3 |
| NCT00856388 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia; Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Aplastic Anemia; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Chronic Myelogenous Leukemia; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Childhood Myelodysplastic Syndromes; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Neutrophilic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; de Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Fanconi Anemia; Juvenile Myelomonocytic Leukemia; Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Paroxysmal Nocturnal Hemoglobinuria; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Splenic Marginal Zone Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Waldenström Macroglobulinemia |
Roswell Park Cancer Institute |
2009-01-14 | |
| NCT00324727 | COMPLETED | Intraocular Melanoma; Melanoma (Skin); Metastatic Cancer |
Delcath Systems Inc. |
2006-02 | PHASE3 |
| NCT00890552 | COMPLETED | Leukemia; Amyloidosis |
Stanford University |
2009-04 | |
| NCT01050764 | TERMINATED | Leukemia, Acute; Chronic Myelogenous Leukemia (CML); Myelodysplastic Syndrome (MDS); Non-Hodgkin Lymphoma (NHL); Chronic Lymphocytic Leukemia (CLL); Acute Myelogenous Leukemia (AML); Acute Lymphoblastic Leukemia (ALL) |
Everett Meyer |
2009-06 | PHASE1; PHASE2 |
| NCT00454480 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
The University of New South Wales |
2006-08 | PHASE2; PHASE3 |
| NCT01160107 | COMPLETED | Multiple Myeloma |
Fondazione EMN Italy Onlus |
2008-07 | PHASE2 |
| NCT00096083 | COMPLETED | Cancer |
Delcath Systems Inc. |
2004-09 | PHASE2 |
| NCT00623077 | TERMINATED | Brain and Central Nervous System Tumors; Kidney Cancer; Liver Cancer; Retinoblastoma; Sarcoma |
Masonic Cancer Center, University of Minnesota |
2005-08 | PHASE1 |
| NCT01350258 | TERMINATED | Hematologic Malignancies; Acute Leukemia; Myelodysplastic Syndromes (MDS) Other Than RA or RARS Subtypes; Hodgkin's Lymphoma; Non-Hodgkin's Lymphoma; Myeloma; Chronic Myelogenous (or Myeloid) Leukemia (CML) Resistant to STI Therapy |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2011-04 | PHASE1; PHASE2 |
| NCT00747877 | UNKNOWN | Multiple Myeloma and Plasma Cell Neoplasm |
Leeds Cancer Centre at St. James's University Hospital |
2008-04 | PHASE3 |
| NCT00857324 | TERMINATED | Multiple Myeloma |
Tiziana Marangon |
2009-03 | PHASE1; PHASE2 |
| NCT00307086 | COMPLETED | Multiple Myeloma; Plasma Cell Leukemia |
H. Lee Moffitt Cancer Center and Research Institute |
2005-06 | PHASE2 |
| NCT00589563 | COMPLETED | Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Infection; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms; Precancerous Condition; Secondary Myelofibrosis; Small Intestine Cancer |
City of Hope Medical Center |
2007-05 | PHASE2 |
| NCT00583622 | TERMINATED | Ovarian Cancer |
M.D. Anderson Cancer Center |
2007-12 | PHASE2 |
| NCT00744536 | COMPLETED | Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Chronic; Angiogenesis |
Sunnybrook Health Sciences Centre |
2008-01 | PHASE2 |
| NCT01532856 | UNKNOWN | Multiple Myeloma |
Grupo de Estudos Multicentricos em Onco-Hematologia |
2007-01 | PHASE3 |
| NCT00020566 | UNKNOWN | Sarcoma |
University of Leicester |
2001-02 | PHASE3 |
| NCT00523809 | TERMINATED | Breast Cancer; Ovarian Cancer |
M.D. Anderson Cancer Center |
2007-08 | PHASE2 |
| NCT00482846 | COMPLETED | Mucositis; Multiple Myeloma |
Barbara Ann Karmanos Cancer Institute |
2007-06 | PHASE1 |
| NCT00972101 | WITHDRAWN | Stem Cell Transplantation; Leukemia; Lymphoma; Pediatric Disorders |
M.D. Anderson Cancer Center |
2009-09 | PHASE1 |
| NCT01359254 | TERMINATED | Hematological Disease |
University of Chicago |
2010-04 | PHASE2 |
| NCT00943293 | TERMINATED | Preleukemia; Myeloproliferative Disorders; Lymphoma; Myeloma; Graft Versus Host Disease |
University of Chicago |
2003-05 | PHASE1 |
| NCT00572897 | COMPLETED | Myelofibrosis |
John Mascarenhas |
2007-08 | PHASE2 |
| NCT00477815 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Mayo Clinic |
2005-05-31 | PHASE1 |
| NCT01055301 | WITHDRAWN | Multiple Myeloma; Plasma Cell Myeloma |
SWOG Cancer Research Network |
2011-07 | PHASE2 |
| NCT00925782 | COMPLETED | Multiple Myeloma |
Acrotech Biopharma Inc. |
2010-01 | PHASE2 |
| NCT00943592 | COMPLETED | Advanced Hematologic Malignancies; Leukemia; Preleukemia |
University of Chicago |
2006-03 | PHASE1; PHASE2 |
| NCT00477035 | COMPLETED | Leukemia; Multiple Myeloma |
Sally Arai |
2006-05 | PHASE1 |
| NCT01213732 | COMPLETED | Patients With Intransit Stage III/IV Melanoma |
Philogen S.p.A. |
2008-10 | PHASE1 |
| NCT00644371 | COMPLETED | Non-Hodgkin Lymphoma |
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea |
2007-11 | PHASE2 |
| NCT00689169 | COMPLETED | Lymphoma, Large Cell, Diffuse |
Lymphoma Study Association |
2007-08 | PHASE2 |
| NCT00907452 | COMPLETED | Myeloma |
Intergroupe Francophone du Myelome |
2009-07-29 | |
| NCT00607984 | UNKNOWN | Central Nervous System Tumors; Tumors |
Rabin Medical Center |
2006-06 | |
| NCT00410631 | UNKNOWN | Neuroblastoma |
German Society for Pediatric Oncology and Hematology GPOH gGmbH |
2004-10 | PHASE3 |
| NCT00427765 | COMPLETED | Multiple Myeloma; Lymphoma |
M.D. Anderson Cancer Center |
2004-12 | PHASE2 |
| NCT00536978 | COMPLETED | Lymphoma; Leukemia |
M.D. Anderson Cancer Center |
2007-09 | PHASE2 |
| NCT00288028 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Barbara Ann Karmanos Cancer Institute |
2005-07 | PHASE1 |
| NCT00427557 | COMPLETED | Multiple Myeloma; Leukemia; Lymphoma |
M.D. Anderson Cancer Center |
2006-10 | PHASE2 |
| NCT00516191 | WITHDRAWN | Multiple Myeloma |
University of California, San Francisco |
2004-10 | PHASE1; PHASE2 |
| NCT00520767 | COMPLETED | Primary Systemic Amyloidosis; Light Chain Deposition Disease |
Barbara Ann Karmanos Cancer Institute |
2007-09 | PHASE2 |
| NCT00772811 | COMPLETED | Chronic Lymphocytic Leukemia; Lymphoma; Multiple Myeloma |
Cooperative Study Group A for Hematology |
2001-07 | PHASE2 |
| NCT00083915 | COMPLETED | Multiple Myeloma |
University of Arkansas |
2001-06 | PHASE3 |
| NCT00723658 | WITHDRAWN | Lymphoma |
SWOG Cancer Research Network |
2008-09 | PHASE2 |
| NCT00003631 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1998-08 | PHASE2 |
| NCT00265889 | COMPLETED | Lymphoma |
Case Comprehensive Cancer Center |
2002-02 | PHASE2 |
| NCT00112645 | COMPLETED | Neuroblastoma; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific |
Milton S. Hershey Medical Center |
2005-04 | PHASE1 |
| NCT00804947 | UNKNOWN | Multiple Myeloma |
Fundacion Para La Investigacion Hospital La Fe |
2005-09 | PHASE2 |
| NCT00244946 | COMPLETED | Lymphoma |
Barbara Ann Karmanos Cancer Institute |
2004-03 | PHASE1 |
| NCT00621400 | COMPLETED | Amyloidosis |
Nantes University Hospital |
2008-01 | PHASE1; PHASE2 |
| NCT00003199 | COMPLETED | Estrogen Receptor-negative Breast Cancer; Estrogen Receptor-positive Breast Cancer; Inflammatory Breast Cancer; Male Breast Cancer; Progesterone Receptor-negative Breast Cancer; Progesterone Receptor-positive Breast Cancer; Stage IIIB Breast Cancer; Stage IV Breast Cancer |
Fred Hutchinson Cancer Center |
1997-11 | PHASE2 |
| NCT00661336 | WITHDRAWN | Melanoma (Skin) |
Duke University |
2008-04 | PHASE1 |
| NCT00547196 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes |
City of Hope Medical Center |
2005-08-16 | |
| NCT00357396 | COMPLETED | Sarcoma |
Memorial Sloan Kettering Cancer Center |
2005-06 | PHASE2 |
| NCT00793650 | TERMINATED | Cancer; Multiple Myeloma |
Emory University |
2005-05 | PHASE1; PHASE2 |
| NCT00054353 | COMPLETED | Refractory Multiple Myeloma |
Fred Hutchinson Cancer Center |
2002-10 | PHASE1; PHASE2 |
| NCT00202917 | COMPLETED | Hematologic Malignancies |
University Hospital Tuebingen |
2004-02 | PHASE1; PHASE2 |
| NCT00508209 | UNKNOWN | Multiple Myeloma |
Nordic Myeloma Study Group |
2007-07 | PHASE2 |
| NCT00038857 | COMPLETED | Leukemia; Lymphoma |
M.D. Anderson Cancer Center |
2001-09 | PHASE2 |
| NCT00417911 | COMPLETED | Multiple Myeloma |
Nordic Myeloma Study Group |
2005-12 | PHASE3 |
| NCT00950768 | COMPLETED | Multiple Myeloma; Diagnosis |
Azienda Ospedaliera San Giovanni Battista |
2002-02 | PHASE3 |
| NCT00349778 | COMPLETED | Multiple Myeloma |
Stanford University |
2006-08 | PHASE2 |
| NCT00027560 | COMPLETED | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Memorial Sloan Kettering Cancer Center |
2001-07 | PHASE2 |
| NCT00185614 | COMPLETED | Blood Cancer; Multiple Myeloma |
Wen-Kai Weng |
2000-08 | PHASE2 |
| NCT00186966 | COMPLETED | Acute Myeloid Leukemia |
Dutch Childhood Oncology Group |
2002-03 | PHASE3 |
| NCT00577668 | WITHDRAWN | Multiple Myeloma |
University of Arkansas |
2007-04 | PHASE2 |
| NCT00434161 | COMPLETED | Multiple Myeloma |
Swedish Orphan Biovitrum |
2006-12 | PHASE3 |
| NCT00421811 | COMPLETED | Neoplasms |
Adherex Technologies, Inc. |
2007-04 | PHASE1; PHASE2 |
| NCT00388999 | COMPLETED | Multiple Myeloma |
Enzon Pharmaceuticals, Inc. |
2006-09 | PHASE1 |
| NCT00789256 | COMPLETED | Acute Myelogenous Leukemia; Myelodysplastic Syndromes |
Dartmouth-Hitchcock Medical Center |
2004-09 | |
| NCT00025103 | UNKNOWN | Kidney Cancer |
Children's Cancer and Leukaemia Group |
2001-05 | PHASE2 |
| NCT00985907 | TERMINATED | Multiple Myeloma; Patient Participation |
University of California, San Francisco |
2004-10-28 | PHASE1; PHASE2 |
| NCT00137995 | COMPLETED | Lymphoma, Large-Cell, Diffuse |
Lymphoma Study Association |
2003-06 | PHASE3 |
| NCT00573391 | TERMINATED | Multiple Myeloma |
University of Arkansas |
2006-08 | PHASE3 |
| NCT00635024 | TERMINATED | Multiple Myeloma and Plasma Cell Neoplasm |
Mayo Clinic |
2008-05 | PHASE2 |
| NCT00160355 | COMPLETED | Wiskott-Aldrich Syndrome |
St. Jude Children's Research Hospital |
2005-05 | PHASE1 |
| NCT00305812 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
NCIC Clinical Trials Group |
2006-03-09 | PHASE2 |
| NCT00104975 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Yale University |
2005-02 | PHASE1 |
| NCT00477750 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Mayo Clinic |
2005-06 | PHASE1; PHASE2 |
| NCT00961467 | COMPLETED | Multiple Myeloma |
Fondazione EMN Italy Onlus |
2007-02 | PHASE2 |
| NCT00074269 | TERMINATED | Breast Cancer |
University of California, San Diego |
2003-07 | PHASE2 |
| NCT00429026 | TERMINATED | Renal Cell Cancer |
M.D. Anderson Cancer Center |
2004-01 | PHASE2 |
| NCT00734149 | COMPLETED | Multiple Myeloma |
Duke University |
2004-07 | PHASE2 |
| NCT00281879 | TERMINATED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms; Unusual Cancers of Childhood |
OHSU Knight Cancer Institute |
2006-02 | PHASE2 |
| NCT00121186 | TERMINATED | Lymphoma |
SWOG Cancer Research Network |
2005-07 | PHASE2 |
| NCT00306735 | COMPLETED | Multiple Myeloma |
Eisai Inc. |
2006-03 | PHASE2 |
| NCT00544570 | COMPLETED | Lymphoma |
City of Hope Medical Center |
1998-04 | |
| NCT00003335 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Case Comprehensive Cancer Center |
1998-01 | PHASE2 |
| NCT00004188 | COMPLETED | Neuroblastoma |
Children's Oncology Group |
2001-02 | PHASE3 |
| NCT01341262 | COMPLETED | Multiple Myeloma |
IRCCS Azienda Ospedaliero-Universitaria di Bologna |
2002-03 | PHASE2 |
| NCT00052884 | TERMINATED | Drug/Agent Toxicity by Tissue/Organ; Multiple Myeloma and Plasma Cell Neoplasm |
Eastern Cooperative Oncology Group |
2004-01-22 | PHASE1 |
| NCT00423709 | COMPLETED | Hodgkin's Disease |
M.D. Anderson Cancer Center |
1998-01 | |
| NCT00313625 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Fred Hutchinson Cancer Center |
2005-09 | PHASE2 |
| NCT00004250 | COMPLETED | Melanoma (Skin); Sarcoma |
Memorial Sloan Kettering Cancer Center |
1999-08 | PHASE2 |
| NCT00135135 | COMPLETED | Neuroblastoma |
St. Jude Children's Research Hospital |
2005-08 | PHASE2 |
| NCT00014469 | COMPLETED | Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Memorial Sloan Kettering Cancer Center |
2000-12 | PHASE2 |
| NCT00290628 | TERMINATED | Chronic Myeloproliferative Disorders; Diamond-blackfan Anemia; Fanconi Anemia; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Masonic Cancer Center, University of Minnesota |
1999-10 | |
| NCT00301860 | TERMINATED | Leukemia; Lymphoma |
University of California, San Francisco |
2003-01 | |
| NCT00443235 | COMPLETED | Multiple Myeloma |
PETHEMA Foundation |
2005-03 | PHASE3 |
| NCT00014508 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Eastern Cooperative Oncology Group |
2001-11-19 | PHASE2 |
| NCT00085449 | WITHDRAWN | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Alliance for Clinical Trials in Oncology |
2006-05 | PHASE1; PHASE2 |
| NCT00089401 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
National Institutes of Health Clinical Center (CC) |
2004-07 | PHASE2 |
| NCT00070200 | COMPLETED | Neuroblastoma |
Children's Oncology Group |
2004-03 | PHASE1 |
| NCT00005792 | COMPLETED | Multiple Myeloma; Plasma Cell Neoplasm |
H. Lee Moffitt Cancer Center and Research Institute |
1998-06-02 | PHASE1 |
| NCT00008190 | COMPLETED | Leukemia |
Herbert Irving Comprehensive Cancer Center |
1999-03 | PHASE2 |
| NCT00002982 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1997-01 | PHASE2 |
| NCT00017368 | COMPLETED | Neuroblastoma |
Children's Oncology Group |
2001-04 | PHASE2 |
| NCT00152126 | COMPLETED | Neuroblastoma; Central Nervous System Tumors; Lymphomas; Wilms Tumor |
St. Jude Children's Research Hospital |
2003-08 | |
| NCT00003632 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1998-09 | PHASE2 |
| NCT00075621 | COMPLETED | Multiple Myeloma |
Boston Medical Center |
2000-08 | PHASE2 |
| NCT00003727 | COMPLETED | Leukemia |
University of Maryland, Baltimore |
1999-03 | PHASE2 |
| NCT00232934 | COMPLETED | Multiple Myeloma |
Gruppo Italiano per lo Studio del Mieloma Multiplo |
2002-01 | PHASE3 |
| NCT00577096 | COMPLETED | Multiple Myeloma |
University of Arkansas |
2001-10 | |
| NCT00002548 | COMPLETED | Multiple Myeloma |
SWOG Cancer Research Network |
1994-01 | PHASE3 |
| NCT00055653 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic-Myeloproliferative Diseases |
Roswell Park Cancer Institute |
2003-01 | PHASE2 |
| NCT00002594 | COMPLETED | Brain Tumor; Central Nervous System Tumor |
Children's Oncology Group |
1994-09 | PHASE2 |
| NCT00003972 | COMPLETED | Breast Cancer |
Fred Hutchinson Cancer Center |
1998-07 | PHASE3 |
| NCT00006747 | COMPLETED | Graft Versus Host Disease; Lymphoma |
Alliance for Clinical Trials in Oncology |
2000-11 | PHASE2 |
| NCT00045136 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Poniard Pharmaceuticals |
2002-01 | PHASE1; PHASE2 |
| NCT00003402 | COMPLETED | Leukemia; Lymphoma |
University of Maryland, Baltimore |
1999-01 | PHASE2 |
| NCT00003396 | COMPLETED | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
University of Maryland, Baltimore |
1998-09 | PHASE2 |
| NCT00003353 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Eastern Cooperative Oncology Group |
1998-11-16 | PHASE2 |
| NCT00003954 | COMPLETED | Refractory Multiple Myeloma; Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma |
Fred Hutchinson Cancer Center |
1999-03 | PHASE1; PHASE2 |
| NCT00003397 | COMPLETED | Lymphoma |
University of Maryland, Baltimore |
1998-09 | PHASE2 |
| NCT00004056 | COMPLETED | Leukemia |
Children's Oncology Group |
1999-10 | PHASE1 |
| NCT00003401 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
University of Maryland, Baltimore |
1999-01 | PHASE2 |
| NCT00003399 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
University of Maryland, Baltimore |
1998-09 | PHASE2 |
| NCT00003926 | TERMINATED | Brain and Central Nervous System Tumors; Childhood Germ Cell Tumor; Chordoma; Kidney Cancer; Liver Cancer; Neuroblastoma; Ovarian Cancer; Retinoblastoma; Sarcoma |
Masonic Cancer Center, University of Minnesota |
1998-11 | PHASE1 |
| NCT00003392 | COMPLETED | Breast Cancer |
UNC Lineberger Comprehensive Cancer Center |
1997-09 | PHASE2 |
| NCT00003425 | COMPLETED | Breast Cancer; Leukemia; Lymphoma; Neuroblastoma; Ovarian Cancer; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific |
University of Kentucky |
1997-12 | PHASE1; PHASE2 |
| NCT00007852 | COMPLETED | Lymphoma |
University of Nebraska |
2000-09-01 | PHASE2 |
| NCT00003081 | COMPLETED | Sarcoma |
Fred Hutchinson Cancer Center |
1998-03 | PHASE1 |
| NCT00002977 | COMPLETED | Ovarian Cancer |
Fred Hutchinson Cancer Center |
1997-01 | PHASE1 |
| NCT00003146 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Fred Hutchinson Cancer Center |
1997-11 | PHASE2 |
| NCT00002750 | COMPLETED | Brain and Central Nervous System Tumors; Extragonadal Germ Cell Tumor; Leukemia; Lymphoma; Ovarian Cancer |
Duke University |
1992-12 | PHASE1 |
| NCT00003086 | TERMINATED | Breast Cancer |
Louisiana State University Health Sciences Center Shreveport |
1997-03 | PHASE1; PHASE2 |
| NCT00002680 | COMPLETED | Breast Cancer |
Yale University |
1994-02 | PHASE2 |
| NCT00003957 | COMPLETED | Lymphoma |
Fox Chase Cancer Center |
1998-12 | PHASE2 |
| NCT00003416 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
1998-09 | PHASE2 |
| NCT00002973 | COMPLETED | Melanoma (Skin) |
University of Wisconsin, Madison |
1995-12 | PHASE2 |
| NCT00003400 | COMPLETED | Prostate Cancer |
University of Maryland, Baltimore |
1998-09 | PHASE2 |
| NCT00003661 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma; Myelodysplastic Syndromes; Neuroblastoma |
Roswell Park Cancer Institute |
1998-06 | PHASE2 |
| NCT00002630 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Mayo Clinic |
1993-06 | PHASE2 |
| NCT00030719 | UNKNOWN | Neuroblastoma |
University of Leicester |
2001-12 | PHASE3 |
| NCT00003007 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
University of Tennessee |
1996-07 | PHASE2 |
| NCT00083564 | TERMINATED | Multiple Myeloma |
Poniard Pharmaceuticals |
2004-03 | PHASE3 |
| NCT00014339 | UNKNOWN | Multiple Myeloma and Plasma Cell Neoplasm |
Medsearch |
2000-03 | PHASE3 |
| NCT00669812 | UNKNOWN | Lymphoma; Small Intestine Cancer |
Cancer Research UK |
2008-02 | PHASE2 |
| NCT00365755 | COMPLETED | Neuroblastoma |
Children's Cancer and Leukaemia Group |
PHASE3 | |
| NCT00001193 | COMPLETED | Breast Neoplasms; Neoplasm Metastasis |
National Cancer Institute (NCI) |
1984-11 | PHASE2 |
| NCT00016887 | UNKNOWN | Lymphoma |
German Low Grade Lymphoma Study Group |
2000-12 | PHASE3 |
| NCT00003578 | UNKNOWN | Lymphoma |
Lymphoma Trials Office |
1993-01 | PHASE3 |
| NCT00181025 | UNKNOWN | Sarcoma of Pelvis |
Gustave Roussy, Cancer Campus, Grand Paris |
2004-05 | PHASE2 |
| NCT00019786 | COMPLETED | Colorectal Cancer; Islet Cell Tumor; Liver Cancer; Metastatic Cancer; Neuroendocrine Carcinoma |
National Institutes of Health Clinical Center (CC) |
1999-08 | PHASE2 |
| NCT00028886 | UNKNOWN | Multiple Myeloma and Plasma Cell Neoplasm |
Commissie Voor Klinisch Toegepast Onderzoek |
2001-03 | PHASE3 |
| NCT00103298 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
National Cancer Institute (NCI) |
2004-12 | PHASE2 |
| NCT00556127 | COMPLETED | Diffuse Large B-Cell Lymphoma; POOR PROGNOSIS |
Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie |
2002-06 | PHASE2 |
| NCT00025649 | COMPLETED | Neuroblastoma |
European Infant Neuroblastoma Study Group - 1999 |
1999-07 | PHASE2 |
| NCT00001587 | COMPLETED | Liver Neoplasms; Neoplasm Metastasis |
National Cancer Institute (NCI) |
1997-09 | PHASE1 |
| NCT00367185 | COMPLETED | Multiple Myeloma |
University Hospital, Lille |
2000-05 | PHASE3 |
| NCT00025064 | UNKNOWN | Lymphoma |
Children's Cancer and Leukaemia Group |
2000-01 | PHASE2 |
| NCT00001296 | COMPLETED | Melanoma |
National Cancer Institute (NCI) |
1992-02 | PHASE3 |
| NCT00020501 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
National Institutes of Health Clinical Center (CC) |
2001-03 | PHASE3 |
| NCT00995059 | WITHDRAWN | Multiple Myeloma; Refractory Multiple Myeloma |
Mayo Clinic |
PHASE1; PHASE2 | |
| NCT01070862 | COMPLETED | Multiple Myeloma de Novo Treatment |
University Hospital, Caen |
2003-05 | PHASE3 |
| NCT00311337 | UNKNOWN | Multiple Myeloma |
University of Wuerzburg |
2005-10 | PHASE2 |
| NCT00027937 | COMPLETED | Lymphoma; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific |
Fred Hutchinson Cancer Center |
2001-08 | PHASE2 |
| NCT00002599 | UNKNOWN | Multiple Myeloma and Plasma Cell Neoplasm |
Medical Research Council |
1994-09 | PHASE3 |
| NCT00002653 | UNKNOWN | Multiple Myeloma and Plasma Cell Neoplasm |
Medical Research Council |
1993-09 | PHASE3 |
| NCT00017225 | COMPLETED | Neuroblastoma |
German Society for Pediatric Oncology and Hematology GPOH gGmbH |
1997-05 | PHASE2 |
| NCT00003603 | UNKNOWN | Multiple Myeloma and Plasma Cell Neoplasm |
Riverside Haematology Group |
1998-03 | PHASE3 |
| NCT00702247 | UNKNOWN | Multiple Myeloma |
Azienda Ospedaliera San Giovanni Battista |
1999-07 | PHASE2 |
| NCT00180791 | UNKNOWN | Medulloblastoma; Brain Tumors; Neuroectodermal Tumors, Primitive |
Gustave Roussy, Cancer Campus, Grand Paris |
2002-07 | PHASE2 |
| NCT00004921 | COMPLETED | Ovarian Cancer |
EBMT Solid Tumors Working Party |
1998-09 | PHASE3 |
| NCT00001576 | COMPLETED | Colorectal Neoplasm; Liver Neoplasm; Neoplasm Metastasis |
National Cancer Institute (NCI) |
1997-07 | PHASE1 |
| NCT00005589 | COMPLETED | Lymphoma |
EBMT Solid Tumors Working Party |
1999-10 | PHASE3 |
| NCT00083876 | COMPLETED | Multiple Myeloma |
University of Arkansas |
1998-09 | PHASE3 |
| NCT00019760 | COMPLETED | Recurrent Colon Cancer; Liver Metastases; Stage IV Rectal Cancer; Recurrent Rectal Cancer; Stage IV Colon Cancer |
National Institutes of Health Clinical Center (CC) |
1999-04 | PHASE2 |
| NCT00001577 | COMPLETED | Melanoma; Sarcoma |
National Cancer Institute (NCI) |
1997-06 | PHASE1 |
| NCT00436761 | UNKNOWN | Unspecified Childhood Solid Tumor, Protocol Specific |
Milton S. Hershey Medical Center |
2004-05 | PHASE1 |
| NCT00004158 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Fred Hutchinson Cancer Center |
1999-06 | PHASE1; PHASE2 |
| NCT00019097 | COMPLETED | Stage II Multiple Myeloma; Stage III Multiple Myeloma; Refractory Plasma Cell Neoplasm |
National Cancer Institute (NCI) |
1995-07 | PHASE2 |
| NCT00008307 | UNKNOWN | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
Herbert Irving Comprehensive Cancer Center |
1998-04 | PHASE2 |
| NCT00417053 | UNKNOWN | Neuroblastoma |
Children's Cancer and Leukaemia Group |
PHASE3 | |
| NCT00358020 | COMPLETED | Multiple Myeloma |
University of Turin, Italy |
2004-11 | PHASE2 |
| NCT00002730 | COMPLETED | Neuroblastoma |
New Approaches to Neuroblastoma Therapy Consortium |
1996-06 | PHASE1 |
(data from https://clinicaltrials.gov, updated on 2025-05-23)
Check the
Melphalan
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Note: Technical data last updated: Sep 1, 2026.