CAS No. 108-78-1
Batch:
Purity:99.99
Chemical Structure
Check the
Melamine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 108-78-1 | |
|---|---|---|
| Molecular Formula |
C3H6N6 |
|
| Molecular Weight (MW) | 126.12 | |
| SMILES | C1(=NC(=NC(=N1)N)N)N |
Melamine is a synthetic triazine compound that acts as a chemical intermediate and exhibits nephrotoxic biological activity. In cellular models, melamine promotes intracellular reactive oxygen species generation and induces oxidative stress in renal tubular epithelial cells. This elevated oxidative stress triggers mitochondrial apoptotic pathways and cellular injury, leading to renal tubular cell dysfunction and contributing to nephrotoxicity. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
25 mg/mL
(198.22 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
25 mg/mL
(198.22 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.